2012, Number 1
<< Back Next >>
Rev Cub Med Mil 2012; 41 (1)
Correlation of TRISS with alterations of opsonocytophagic index of injured patients
Rodríguez ND, Rodríguez AM, Alfonso ALE, Quintana RM, Catellanos PE, Garcés SY
Language: Spanish
References: 29
Page: 48-57
PDF size: 170.89 Kb.
ABSTRACT
Introduction: the injured patient under stress due to multiple causes (physical, emotional and surgical), has from very early stages, significant alterations in the immune response.
Objective: to assess the "trauma injury severity score" (TRISS) predictive index haw indicating of phagocytic ability status of the neutrophiles poly-morphonuclear leucocytes.
Methods: an analytical and prospective study was conducted in 55 injured patients admitted in the "Dr. Luis Díaz Soto" Central Military Hospital from 2005 to 2008. Immunological tests were applied where the more important ones were the immunological variables, the TRISS-survival probability, complications and status at discharge. Different statistic methods were used.
Results: there was predominance of infectious complications. In the deceased ones, the immunity depletion was the more significant. Insofar as the survival decreased, according TRISS, the opsonocytophagic index was affected. The immunological alterations were more intensive in deceased ones and in those with poor diagnosis. The great immunity affections occurred over the first week.
Conclusions: TRISS has a predictive role in the prognostic index for these alterations.
REFERENCES
Larrea Fabra ME. Historia de la cirugía del trauma. Rev Cubana Cir [Internet]. 2007 [citado 17 Feb 2010];46(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-74932007000400011&lng=es&nrm=iso&tlng=es
Mortalidad. En: Anuario Estadístico de Salud 2008. Ciudad de La Habana: Ministerio de Salud Pública. Dirección Nacional de Registros Médicos y Estadística de Salud; 2009. p. 27-92.
Rodríguez Suárez G, Mesa Menéndez M, Ponz Moscoso F, Valdivia Puerta A, Mur Villar N. Valoración de la atención de urgencias al paciente con trauma grave. Rev Cubana Cir. 2002;41(3):185-93.
Shires GT, Thal ER, Jones RC, Shires III GT, Perry MO. Traumatismos. En: Schwartz SI, Shires GT, Spencer FC. Principios de Cirugía. 6ª ed. México, DF: McGraw-Hill Interamericana; 1995. p. 179-229.
Comité de Trauma del Colegio Americano de Cirujanos. Generalidades del curso: El propósito, la historia y conceptos del programa ATLS para médicos. En: Curso avanzado de apoyo vital en trauma para médicos. Comité de Trauma del Colegio Americano de Cirujanos: Chicago; 1994. p. 9-17.
Ramírez Medina S, Gutiérrez Vázquez IR, Domínguez Maza A, Barba Fuentes C. Respuesta metabólica al trauma. MEDICRIT. 2008;5(4):130-3.
Marianne A, Waxman K. Soluble cytokine receptors and receptor antagonists are sequentially released alter trauma. J Trauma. 1995;39(1):2-4.
Faist E, Wichmann M, Baue A. La respuesta inmunitaria. En: Mattox KL, Feliciano DV, Moore EE. Trauma. México, DF: McGraw-Hill Interamericana; 2001. p. 1507-25.
Hietbrink F, Koenderman L, Rijkers G. Trauma: the role of the innate immune system. World J Emerg Surg [Internet]. 2006 [cited 2010 Mar 2011];1(15). Available from: http://www.wjes.org/content/1/1/15
Pillay J, Hietbrin KF, Koenderman L, Leenen LP. The systemic inflammatory response induced by trauma is reflected by multiple phenotypes of blood neutrophils. Injury. 2007;38(12):365-72.
Toumi H, F´guyer S, Best TM. The role of neutrophils in injury and repair following muscle stretch. J Anat. 2006;208(4):459-70.
Tschoeke SK, Hellmuth M, Hostmann A, Ertel W Oberholzer A. The Early Second Hit in Trauma Management Augments the Proinflammatory Immune Response to Multiple Injuries. J Trauma. 2007;62(6):1396-404.
Pap G, Furész J, Fennt J, Kovács GC, Nagy L, Hmar J. Self-regulation of neutrophils during phagocytosis is modified after severe tissue injury. J Mol Med. 2006;17(4):649-54.
Pillgram-Larsen J, Marcus M, Svennevig JL. Assessment of probability of survival in penetrating injuries using the TRISS methodology. Injury. 1989;20(1):10-2.
Civil ID. The Abbreviated Injury Scale. Revition: a condensed chart of clinical use. J Trauma. 1988;28(1):87-90.
Boyd CR, Tolson MA, Copes WS. Evaluating Trauma Care: The TRISS Method. J Trauma. 1987;27(4):370-8.
Champion HR, Sacco WJ, Cornazzo AJ, Copes WS, Fouty WJ. Trauma Score. Crit Care Med. 1981;9(9):672-6.
Champion HR, Sacco WJ, Hunt TK. Trauma severity scoring to predict mortality. World J Surg. 1993;7(1):4-11.
Manual del SPSS. Guía para el análisis de datos versión 17.00 para el Windows. Madrid: Hispanoportuguesa/SPSS [Internet]. 2008 [citado 27 Ago 2009]. Disponible en: http://www.emagister.com/guia-rapida-spss-para-windows-cursos-1076231.htm
Cox DR, Hinkely DV. Theoretical statistics. New York: Chapman and Hall Ltd; 1974. p. 11-56.
Canavos GC. Probabilidad y estadística. Aplicaciones y métodos. La Habana: Editorial Félix Varela; 2006. p. 303-53.
Guyton AC. Resistencia del organismo a la infección: I. Leucocitos, granulocitos, el sistema macrófago-monocito e inflamación. En: Guyton AC, Hall JE. Tratado de Fisiología Médica. 10a ed. La Habana: Editorial Ciencias Médicas; 2008. p. 477-87.
Guyton AC. Resistencia del organismo a la infección: II. Inmunidad y alergia. En: Guyton AC, Hall JE. Tratado de Fisiología Médica. 10a ed. La Habana: Editorial Ciencias Médicas; 2008. p. 489-501.
Peña Martínez J. Células inmunocompetentes. En: Peña Martínez J. Inmunología. Madrid: Ediciones Pirámide; 1998. p. 47-61.
Rodríguez Acosta M, Vázquez González T, Castellanos Puerto E, Alfonso Alfonso LE, Rojas Moya A, Jonnston Dreke N. Evaluación inmunológica del paciente politraumatizado. Rev Cubana Med Milt. 2000;29(1):12-9.
Collins T. Inflamación aguda y crónica. En: Cotran RS. Robbins. Patología estructural y funcional. Madrid: Interamericana; 1999. p. 53-93.
Sweeney JF, Rosemurgy AS, Wei S, Djeu JY. Impaired polymorphonuclear leukocyte anticandidal function in injured adults with elevated candida antigen titers. Arch Surg. 1993;128(1):40-6.
Sin Mayor A, Castellanos Puerto E, Rodríguez Acosta M, Vázquez González T, Jonhston Dreke N, Rojas Moya A. Alteraciones del mecanismo de la fagocitosis en el paciente lesionado. Rev Cubana Med Milt. 2000;29(2):109-13.
Turina M, Hotle JJ, Turpen RM, Scout MJ, Cheadle WG. Alveolar interleukin-10 regulates neutrophil appoptosis in several traumatized patients. J Trauma. 2007;63(4):733-9.