2011, Number 2
<< Back Next >>
Rev Cubana Invest Bioméd 2011; 30 (2)
Obesity and colorectal cancer risk
Hano GOM, Wood RL, Villa JOM
Language: Spanish
References: 27
Page: 251-259
PDF size: 136.19 Kb.
ABSTRACT
Obesity is a chronic and multifactor disease characterized by presence of excess
body fat harmful for health. Several studies have been conducted to assess the
possible risk character of different factors for colorectal cancer including the
following modifying factors: a diet rich in saturated fats, a diet low in vegetables,
physical inactivity, alcohol consumption and obesity. A case-control study was
conducted to include 276 adult patients (93 cases and 184 controls) consecutively
seen from May, 2008 to May, 2009 in the Institute of Gastroenterology determining
a possible association between obesity as risk factor and colorectal cancer.
Variables measures included: sex, age, skin color, body mass index, hip-waist
circumference and endoscopic location of cancer. We conclude that the colorectal
cancer with predominance in female sex and in white people in both groups.
Obesity according to a great relation hip-waist had an strong relation with colorectal
cancer, which had predominance towards distal colon in both sexes.
REFERENCES
Organización Panamericana de la Salud. Obesidad y sobrepeso. Report of a WHO Consultation on Obesity. World Health Organization (WHO). Nota descriptiva No. 311; 2000.
Porrata C, Rodríguez-Ojea A, Jiménez S. La Transición Epidemiológica en Cuba. En: La Obesidad en la Pobreza. Washington: OPS; 2000. p. 62-64.
Bray GA. Obesidad. Organización Panamericana de la Salud, Instituto Internacional de Ciencias de la Vida. Conocimientos actuales sobre nutrición. Washington, DC: OPS, ILSI; 1997. p. 27-33.
Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K. General and Abdominal Adiposity and Risk of Death in Europe. NEJM. Nov. 2008;359(20):2105-20.
Alfonzo Guerra JP. Obesidad. Epidemia del siglo XXI. La Habana: Editorial Científico-Técnica; 2008.
Zosia Chustecka, Désirée Lie. Excess Body Weight Increases Risk for Many Cancers CME/CE. Lancet. 2008;1371:536-7.
Larsen IK, Grotmol T, Almendiguer K, Hoff G. Lifestyle as a predictor for colonicneoplasm in asymptomatic individuals. BMC Gastroenterology. 2006;6:5.
Rainoldi JL. Epidemiología del Cáncer Colorrectal. Avances en la Gastroenterología en las Américas. Lima: Edit. CIMAGRAF; 2005. p. 162.
Giovannucci E. Metabolic syndrome, hyperinsulinemia, and colon cancer: a review. Am J Clin Nutrition. 2007;86(3):836S-842S.
Hernández Triana M, Porrata Maury C. Calcio, osteoporosis, hipertensión arterial y cáncer colorrectal. Rev Cubana Aliment Nutr. 1999;13(1):33-45.
Calle EE. Obesity and cancer. BMJ. 2007;335:1107-8.
Frezza EE, Wachtel MS, Chiriva-Internati M. Influence of obesity on the risk of developing colon cancer. Gut. 2006;55:285-91.
Polednak AP. Trends in incidence rates for obesity-associated cancers in the U.S. Cancer Detection and Prevention. 2003;27(6):41521.
Obesidad y cáncer: preguntas y respuestas. (National Cancer Institute). 2009. [citado 22 de julio de 2009]. Disponible en: http://www.cancer.gov/espanol/cancer/hojas-informativas/obesidad-respuestas
Patel M, Cipher D. Prevalence of obesity, central obesity and the associated factors in urban population aged. Obes Rev. 2007:10-4.
Potter JD, Slattery ML, Bosteck RM. Colon Cancer: a review of the epidemiology. Epidemiol Rev. 2006;15:499-545.
Shinchi K, Kono S, Sakurai Y. Obesity and adenomatous polyps of the sigmoid colon. Japan J Cancer Res. 2005;85:479-84.
Berdasco A, Romero JM. Analysis and interpretation of Cuban adult anthropometry based on some classification variables. (Nutrition Consultants Report Series;No.88). Rome: FAO; 1992.
Jiménez S, Díaz ME, Barroso I, Bonet M, Cabrera A, Wong I. Estado nutricional de la población cubana adulta. Revista Española Nutrición Comunitaria. 2005;11(1):18-28.
Thygesen LC. Weight Gain in Adulthood Increases Risk of Colon Cancer in Men. Int J Cancer. 2008;123:1160-5.
Mueller PS. Increasing BMI Is Associated with Increased Cancer Risk and Mortality in Women. BMJ. 2007 Dec;335:1134.
Cohen SS, Palmieri RT, Nyante SJ, Koralek DO, Kim S, Bradshaw P, et al. Obesity and screening for breast, cervical, and colorectal cancer in women: a review. Cancer. 2008;112(9):1892-904.
Cameron AJ, Dunstan DW, Owen N, Zimmet PZ, Barr EL, Tonkin A. Health and mortality consequences of abdominal obesity: evidence from the Aus Diab study. Med J Aust. 2009;191(4):202-8.
Yumuk PF, Dane F. Impact of body mass index on cancer development (Cancer Causes control). J Boun. 2008 Jan-Mar;13(1):55-9.
Pischon T, Lahmann PH, Boeing H, Friedenreich C, Norat T, Tjonneland A, et al. Body size and risk of colon and rectal cancer in the European prospective investigation into cancer and nutrition (EPIC). J Natl Cancer Inst. 2006;98(13):920-31.
Larsson SC, Wolk A. Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies. Am J Clin Nutrition. September 2007;86(3):556-65.
Food, Nutrition, Physical Activity, and the Prevention of Cancera Global PerspectiveOnline. WCRF/AICR. 2007. [cited Oct 2009]. Available from: http://www.dietandcancerreport.org/