2012, Number 1
<< Back Next >>
Bol Clin Hosp Infant Edo Son 2012; 29 (1)
Prevalence for Possible Donors from Umbilical Cord Blood
Rendón-García H, Covarrubias-Espinoza G, Rojo-Quiñonez AR, Galicia-Hernández M
Language: Spanish
References: 24
Page: 13-18
PDF size: 82.37 Kb.
ABSTRACT
Introduction: In recent years the production of hematopoietic cells, derived from umbilical cord blood (UCB), has been increasing worldwide as a treatment for various diseases.
Objective: To know the prevalence of quality gynecological and neonatal in pregnant women for potential donors of UCB.
Material and Methods: A cross-sectional retrospective study 360 infants and pregnant women in a probability sample. Normal pregnancies were included to value quality obstetric and neonatal UCB donation, according to the Mexican bank of umbilical cord questionnaire. We calculated the prevalence of donation and analyzed by Chi2 test, analysis based on the program NCSS 2007.
Discussion: We estimated 67% of potential donors based on the number of births per year. Features like normal labor, newborn healthy weight, adequate prenatal care, risk partner, multiparity, healthy pregnancy as possible donors. We were unable to evaluate important factors such as the use of tobacco, alcohol, drugs, tattoos, tuberculosis and HIV.
Conclusions: Quality obstetric and neonatal in pregnant women for possible donation by 67% SCU was recorded. This makes an important number of SCU could lead to a cryopreservation program well directed in the future.
REFERENCES
Ornelas-Sánchez MA. El trasplante de progenitores hematopoyéticos una necesidad en el tratamiento del cáncer infantil en el Hospital Infantil del Estado de Sonora. Tesis de especialidad. Enero 2008.
Martínez Carlos (2003). Simposio de banco de cordón, hacia la excelencia. Gaceta de Médicina México Vol.139, No. 3. 93-103.
Ballen KK, Wilson M, Wuu J, Ceredona AM y cols (2001). Bigger is better: maternal and neonatal predictors of hematopoietic potential of umbilical cord blood units. Bone Marrow Transplantation. Vol 27, 7–14.
Solves P, Perales A, Mirabet V, Blasco I y cols (2004). Optimizing donor selection in a cord blood bank. European Journal of Haematology. Vol. 72: 107–12.
Donaldson C, Buchanan R, Webster J, Laundy V y cols (2005). Development of a district Cord Blood Bank: a model for cord blood banking in the National Health Service American Academy of Pediatrics. Bone Marrow Transplantation. Vol 25, 899–905.
Novelo G, Limon F, Guerra M, Luna B y cols (2008). Establishing a cord blood banking and transplantation programming Mexico: a single institution experience. Transfusión. Vol 48, 228-36.
Solves P, Perales A, Mirabet V, Blasco I y cols (2004). Optimizing donor selection in a cord blood bank. European Journal of Haematology. Vol. 72: 107–12.
http://www.slideshare.net/many87/example-of-mother-health-questionnaire. Julio 27 del 2011; 8:00hrs.
Shelbak A, Roberts I, Stevens T, Syzdlo M, Goldman J y Gordon M (1998). The impact of antenatal and perinatal variables on cord blood haemopoietic stem/progenitor cell yield available for transplantation. British Journal of Haematology, 103, 1167–71.
American Academy of Pediatrics (2007). Cord Blood Banking for Potential Future Transplantation. Oficial Journal of the American Academy of Pediatrics. Vol 119; 165-70.
Anthony Armson B. y cols (2005). Umbilical Cord Blood Banking: Implications for Perinatal Care Providers. Clinical Practice Guidelines.
Calderón Garcidueñas Eva (2005). Evaluación del Programa Nacional de sangre placentaria CordMX. Revista Médica del Instituto Mexicano del Seguro Social; 43 (Supl 1): 127-9.
Calderón Garcidueñas Eva (2009). Propuesta de un nuevo modelo de banco de sangre de cordón umbilical para América Latina. Revista mexicana de patología clínica Vol. 56, N.4, pp 271-7.
Cohen Yossi and Nagler Arnon (2003). Hematopoietic Stem-cell Transplantation Using Umbilical-cord-Blood. Leukemia & Lymphoma, Vol. 44, No 8., pp. 1287–99.
Gaya A, Lareo A, Hernandez M, Barbolla L y cols (2008). Plan Nacional de Sangre de Cordón Umbilical. Organización Nacional de Trasplantes.
Gluckman E, Rocha V, Arcese W, et al; Eurocord Group(2004). Factors associated with outcomes of unrelated cord blood transplant: guidelines for donor choice. Exp Hematol; 32: 397-407.
NetCord/Fact (2001). International standards for cord blood collection, processing, testing, banking, selection and release. 2nd ed.
Patsy L, PA-C, McGadney D, MSW, Hampton J (2010) Educating patients about the value of umbilical cord blood donation. JAAPA. 23 (11).
Oudshoorn M, Horn P, M. Tilanus (2007). Typing of potential and selected donors for transplant: methodology and resolution. Journal compilation 69 Suppl. 1 (10–12).
Plaza F, Espinoza L, Colmenares G, Plaza R. (2002). Usos de la placenta y del cordón umbilical. Gaceta Médica de Caracas v.110 n.2 367-80.
Serrano Delgado Mosises, Novello Garza Barbara and Valdez Martinez Edith (2009). Ethical issues relating to the banking of umbilical cord blood in Mexico. BMC Medical Ethics .10:12
Rubinstein P, Adamson JW, Stevens C (1999). The Placental/Umbilical Cord Blood Program of the New York Blood Center. A progress report. Ann N Y Acad Sci 872; 328.
Donaldson C, Armitage W, Laundy V, Barron C y cols (1999). Impact of obstetric factors on cord blood donation for transplantation. Br J Haematol; 106: 128–32.
Saltiel Chirsiane (2010). Bancos de sangre placentaria: ¿públicos o privados? Revista de Hematología .Vol. 11(2):123-31.