2012, Number 6
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Arch Med Actual Trac Gen Inf 2012; 4 (6)
Candidiasis Vulvovaginal Recurrente: Nuevos protocolos terapéuticos
Briseño HH
Language: Spanish
References: 17
Page: 12
PDF size: 427.94 Kb.
ABSTRACT
The recurrent vulvovaginal candidiasis tends to increase and in clinical practice has become a challenge, clinical
manifestations ranging from asymptomatic colonization to severe symptoms. It also requires the accurate clinical
diagnosis: Display blastospores or pseudohyphae microscopy in saline or 10% KOH and culture positive in symptomatic women. 15% of fungal infections evolve recurrent vulvovaginal candidiasis and about 85% of cases are caused by Candida albicans no. Concomitant morbidity such as diabetes mellitus, corticosteroids or long-term
antimicrobial therapy, immunosuppressive states such as pregnancy and yeast colonization of the gastrointestinal
tract often coincide with recurrent vulvovaginal candidiasis. Therapeutic options contemplated induction therapy and maintenance, antifungal drugs fluconazole and itraconazole are recommended to different protocols for prolonged periods up to 6 months, the results of clinical and mycological cure ranging from 49.6% to 90%. Fluconazole showed the different treatment protocols in an antifungal be effective for patients with recurrent fungal vulvovaginitis in numerous clinical trials, with good tolerance and broad therapeutic range of a single dose.
REFERENCES
Patel DA, Sobel JD. Am J Obstet Gynecol. 2004 Mar;190(3):644-53
Ray A, Cochrane Database Syst Rev. 2011 Aug 10;(8)
Anderson MR, Klink K, Cohrssen A. Evaluation of vaginal complaints. JAMA 2004;291:1368-79.
ACOC Practice Bulletin. Clinical management guidelines for obstetrician-gynecologists. Number 72, May 2006: Vaginitis. Obstet Gynecol. 2006: 107(5):1195-1206.
Sex transm Infect. 2006, december 82; (4) 28-30
NOM-039-SSA2-2002 para la prevención y control para las infecciones de transmisión sexual.
Guías de práctica clínica (GPC) IMSS-081-08. Diagnostico y tratamiento de la vaginitis infecciosa en mujeres en edad reproductiva en un primer nivel de atención.
Sobel JD, et al. Treatment of complicated Candida vaginitis: comparison of single and sequeuntial doses of fluconazole. Am J Obstet Gynecol 2001;185:363-9.
Sobel JD, et al. Maintenance fluconazole therapy for recurrent vulvovaginal candidiasis N Engl J Med2004;351:87- 83.
Kotarski J, et al. Treatment of acute and recurrent vulvovaginal candidiasis. Ginekol Pol. 2008 Sep;79(9):638- 52.
Borisov I. Akush Gynekol.2005; 44(2) 17-20
Ventolini G. J Reprod Med 2006; 51(6) 475-8
Donders G. Individualized decresing-dose maintenance fluconazole regimen for recurrent vulvovaginal candidiais. Am J Obstet Gynecol 2008, Dec; 199(6):613.
Murina F. Graziottin A, Felice R, Radici GL, Di Francesco S. The recurrent Vulvovaginal Candidiasis: Proposal of a personalized Therapeutic Protocol. ISRN Obstetrics and Gynecoly; 2011. Epub 2011 Aug 9.
Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention. Recomm Rep 2002;51(RR-6):1-78.
Lavazzo C. Boric Acid for recurrent vulvovaginal candidiasis: the clinical evidence. J Womens Health. 2011 Aug;20(8):1245-55.
Hanley-Belfus, 2003, Tercera edición OB/GYN SECRETS