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2011, Number 3

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Rev Cuba Endoc 2011; 22 (3)

Frequency and characterization of metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1 diabetes

Parlá SJ, Cabrera RE, Marichal MS, Arranz CC, Domínguez AE, González FP, Vera GM

Language: Spanish
References: 45
Page: 196-209
PDF size: 95.83 Kb.


ABSTRACT

Introduction: the metabolic syndrome is defined as the association of some factors causing cardiovascular disease and of type 2 diabetes mellitus.
Objective: to determine the frequency of the metabolic syndrome according to the criteria of the International Federation of Diabetes in first degree relatives of persons with type 1diabetes.
Methods: ninety six adults and 97 adolescents were selected to apply a questionnaire and a general physical examination. Also, assessment of fast glucose, insulin, cholesterol, triglycerides and HDL-cholesterol were carried out, estimating the rate of insulin-resistance.
Results: the frequency of metabolic syndrome was higher in adults for a 17,7 % (17/96) than in adolescents for a 3,09 % (3/97) and the insulin resistance in adults was similar in those subjects with and without metabolic syndrome. The family history of cardiovascular disease, type 2 diabetes mellitus, obesity, dyslipemia and high blood pressure is not associated with the presence of metabolic syndrome in first degree relative of persons with type 1 diabetes.
Conclusions: the metabolic syndrome, according the criteria of the International Federation of Diabetes, is more frequent in adult persons than in the adolescent first degree relatives of persons with type 1 diabetes and that the insulin resistance in these subjects is not exclusively associated with the metabolic syndrome.


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