medigraphic.com

2012, Number 1

<< Back Next >>

Cir Cir 2012; 80 (1)

Lung transplantation with uncontrolled non-heart-beating donor. Review

Munguía-Canales DA, Campo-Cañaveral de la Cruz JL, Crowley-Carrasco S, Lazo-Pérez D, Macías-Sotuela L, Varela-de Ugarte A

Language: Spanish
References: 41
Page: 86-91
PDF size: 374.24 Kb.


ABSTRACT

The discrepancy between organ availability and the increasing amount of patients on the waiting list has prompted the development of medical strategies to increase the usable organs, including the search for alternative sources of donation, organ optimization and extension of the criteria for donation.
The recovery of lungs from non-heart-beating donors (NHBD) is a concept in which death is declared based on cardiopulmonary criteria rather than the currently used definition of “brain death.”
Obtaining NHBD lungs is currently practiced in many centers. In this review we discuss the current state of lung transplantation from uncontrolled NHBD.


REFERENCES

  1. Bernat JL, D’Alessandro AM, Port FK, Bleck TP, Heard SO, Medina J, et al. Report of a National Conference on Donation after cardiac death. Am J Transplant 2006;6:281-291.

  2. Steinbrook R. Organ donation after cardiac death. N Engl J Med 2007;357:209-213.

  3. Recommendations for non-heart-beating organ donation. A position paper by the Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 2001;29:1826-1831.

  4. Kootstra G, Daemen JH, Oomen AP. Categories of non-heart-beating donors. Transplant Proc 1995;27:2893-2894.

  5. Kootstra G. Statement on nonheart-beating donor programs. Transplant Proc 1995;27:2965.

  6. Ulicny KS Jr, Egan TM, Lambert CJ Jr, Wilcox BR. Cadaver lung donors: effect of preharvest ventilation on the graft function. Ann Thorac Surg 1993;55:1185-1191.

  7. Avlonitis VS, Fisher AJ, Kirby JA, Dark JH. Pulmonary transplantation: the role of brain death in donor lung injury. Transplantation 2003;75:1928-1933.

  8. Inci I, Arni S, Acevedo C, Jungraithmayr W, Inci D, Vogt P, et al. Surfactant alterations following donation after cardiac death donor lungs. Transpl Int 2010:78-84 (pendiente de publicación).

  9. Neyrinck AP, Van De Wauwer C, Geudens N, Rega FR, Verleden GM, Wouters P, et al. Comparative study of donor lung injury in heart-beating versus non heart-beating donors. Eur J Cardiothorac Surg 2006;30:628-636.

  10. Egan TM, Lambert CJ Jr, Reddick R, Ulicny KS Jr, Keagy BA, Wilcox BR. A strategy to increase the donor pool: use of cadaver lungs for transplantation. Ann Thorac Surg 1991;52:1113-1120.

  11. Kutschka I, Sommer SP, Hohlfeld JM, Warnecke G, Morancho M, Fischer S, et al. In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model. Eur J Cardiothorac Surg 2003;24:411.

  12. Rega FR, Neyrinck AP, Verleden GM, Lerut TE, Van Raemdonck DE. How long can we preserve the pulmonary graft inside the nonheart-beating donor? Ann Thorac Surg 2004;77:438-444.

  13. Inci I, Arni S, Inci D, Zhai W, Hillinger S, Leskosek B, et al. Impact of topical cooling solution and prediction of pulmonary graft viability from non-heart-beating donors. J Heart Lung Transplant 2008;27:1016-1022.

  14. Shimada K, Kondo T, Handa M, Okada Y, Ohura H, Hirose M, et al. The possibility of lung transplantation from non-heart-beating donors: experimental study in a canine model. Transplant Proc 1994;26:880-881.

  15. Buchanan SA, DeLima NF, Binns OA, Mauney MC, Cope JT, Langenburg SE, et al. Pulmonary function after non-heart-beating lung donation in a survival model. Ann Thorac Surg 1995;60:38-44.

  16. Greco R, Cordovilla G, Sanz E, Benito J, Criado A, Gonzalez M, et al. Warm ischemic time tolerance after ventilated nonheart-beating lung donation in piglets. Eur J Cardiothorac Surg 1998;14:319-325.

  17. Bertolotti A, Gomez C, Lascano E, Negroni J, Cuniberti L, Yannarelli G, et al. Effect of preservation solution on graft viability in singlelung transplantation from heart-beating donors in pigs. Transplant Proc 2007;39:355-357.

  18. Gamez P, Varela A, Tellez JC, Castedo E, Rodríguez-Roda J, García C, et al. Bifasic graft preservation for lung transplantation (in Spanish). Arch Bronconeumol 1998;34:417-420.

  19. Struber M, Hohfeld JM, Kofidis T, Warnecke G, Niedermeyer J, Sommer SP, et al. Surfactant function in lung transplantation after 24 h of ischemia: advantage of retrograde flush perfusion for preservation. J Thorac Cardiovasc Surg 2002;123:98-103.

  20. Varela A, Cordoba M, Serrano-Fiz S, Burgos R, Montero CG, Téllez G, et al. Early lung allograft function after retrograde and antegrade preservation. J Thorac Cardiovasc Surg 1997;114:1119-1120.

  21. Van De Wauwer C, Neyrinck AP, Geudens N, Rega FR, Verleden GM, Verbeken E, et al. Retrograde flush following topical cooling is superior to preserve the nonheart-beating donor lung. Eur J Cardiothorac Surg 2007;31:1125-1133.

  22. Hardy JD, MoynihanPC, Timmis HH, Chavez CM, Davis JT Jr, Anas P. A case of clinical lung allotransplantation. J Thorac Cardiovasc Surg 1970;60:411-426.

  23. Wildevuur CR, Benfield JR. A review of 23 human lung transplantations by 20 surgeons. Ann Thorac Surg 1970;9:489-515.

  24. Love RB, Stringham J, Chomiak PN, Pellet JR, Mentzer RM. First successful lung transplantation using a nonheart-beating donor. J Heart Lung Transplant 1995;14:S88.

  25. D’Alessandro AM, Fernandez LA, Chin LT, Shames BD, Turgeon NA, Scott DL, et al. Donation after cardiac death: the University of Wisconsin experience. Ann Transplant 2004;9:68-71.

  26. D’Alessandro AM, Hoffmann RM, Knechtle SJ, Eckhoff DE, Love RB, Kalayoglu M, et al. Successful extrarenal transplantation from non-heart-beating donors. Transplantation 1995;59:977-982.

  27. Steen S, Ingemansson R, Budrikis A, Bolys R, Roscher R, Sjöberg T. Successful transplantation of lungs topically cooled in the non-heartbeating donor for 6 h. Ann Thorac Surg 1997;63:345-351.

  28. Steen S, Sjoberg T, Pierre L, Liao Q, Eriksson L, Algotsson L. Transplantation of lungs from a non-heart-beating donor. Lancet 2001;357:825-829.

  29. Steen S, Ingemansson R, Eriksson L, Pierre L, Algotsson L, Wierup P, et al. First human transplantation of a nonacceptable donor lung after reconditioning ex vivo. Ann Thorac Surg 2007;83:2191.

  30. Aigner C, Klepetko W. Lung transplantation using donors after cardiac death. Curr Opin Organ Transplant 2007;12:459-463.

  31. Nunez JR, Varela A, del Rio F, Gámez P, Calatayud J, Córdoba M, et al. Bipulmonary transplants with lungs obtained from two nonheartbeating donors who died out of hospital. J Thorac Cardiovasc Surg 2004;127:297-299.

  32. Gamez P, Cordoba M, Ussetti P, Carreño MC, Alfageme F, Madrigal L, et al., Lung Transplant Group of the Puerta de Hierro Hospital. Lung transplantation from out-of-hospital nonheart-beating lung donors. One-year experience and results. J Heart Lung Transplant 2005;24:1098-1102.

  33. de Antonio DG, Marcos R, Laporta R, Mora G, García-Gallo C, Gámez P, et al. Results of clinical lung transplant from uncontrolled nonheart-beating donors. J Heart Lung Transplant 2007;26:529-534.

  34. de Antonio DG, de Ugarte AV. Present state of nonheart-beating lung donation. Curr Opin Organ Transplant 2008;13:659-663.

  35. Matesanz R, Domínguez-Gil B. Organización del trasplante en España. En: Cuervas-Mons MV. Introducción al Trasplante de Organos y Tejidos. Spain: Tile Von, 2009. pp. 30-31.

  36. Online. Organización Nacional de Trasplantes. Trasplante Pulmonar. Memoria de Actividad. ONT 2009. Disponible en: http://www.ont.es/infesp/Memorias/Memoria_Pulmon_2009.pdf.

  37. Egan TM. Non-heart-beating donors in thoracic transplantation. J Heart Lung Transplant 2004;23:3.

  38. Egan TM, Haithcock JA, Nicotra WA, Koukoulis G, Inokawa H, Sevala M, et al. Ex vivo evaluation of human lungs for transplant suitability. Ann Thorac Surg 2006;81:1205-1213.

  39. Inokawa H, Sevala M, Funkhouser WK, Egan TM. Ex-vivo perfusion and ventilation of rat lungs from non-heart-beating donors before transplant. Ann Thorac Surg 2006;82:1219-1225.

  40. Cype lM, Yeung JC, Hirayama S, Rubacha M, Fischer S, Anraku M, t al. Technique for prolonged normothermic ex vivo lung perfusion. J Heart Lung Transplant 2008;27:1319-1325.

  41. Moradiellos DFJ, Varela A. Perfusión ex vivo: evaluar, recuperar y optimizar pulmones humanos para trasplante. Arch Bronconeumol 2010;46:213-214.




2020     |     www.medigraphic.com