2012, Number 03
<< Back Next >>
MediSan 2012; 16 (03)
Transfusion requirements in a polyvalent intensive care unit for adults
Cruz PA, Ramírez ZM, Jardines GE, Ricardo MC
Language: Spanish
References: 20
Page: 392-400
PDF size: 200.85 Kb.
ABSTRACT
Introduction: Blood transfusion is a common practice in intensive care units.
Objective: To determine the transfusion need of 382 critically ill patients hospitalized in
this service.
Methods: A descriptive and retrospective study was carried out in these
cases that were not expected to die in the first 24 hours of being admitted to "Vladímir
Ilich Lenin" Polyvalent Intensive Care Unit in Holguín during 2010. Clinical
epidemiological variables were analyzed by means of the chi-square tests and Student's t
test (alpha=0.05).
Results: Of all the series the majority were men (51.6%), the mean
age was 54±21 years, and deaths constituted 35.1% and mean hospital stay was found
to be 7.2±8.4 days. Red cell transfusion was applied to 23.3%, and fresh plasma,
platelets and cryoprecipitate to 12.6%; 4.5 and 5.2% respectively. Each patient received
3.3±3.9 transfusions, although those of red blood cells and fresh plasma became higher
and lower levels of pretransfusion hemoglobin in those who died. Among the major
complications were hospital infections and acute renal failure with prevalence in
transfused patients, who had longer stays.
REFERENCES
Napolitano LN. Scope of the problem: epidemiology of anemia and use of blood transfusions in critical care. Crit Care. 2004;8(Suppl 2):1-8.
Douay L, Andreu G. Ex vivo production of human red blood cells from hematopoietic stem cells: What is the future in transfusion? Transfus Med Rev. 2007;21(2):91-100.
Greenburg AG. The ideal blood substitute. Crit Care Clin. 2009;25(2):415–24.
Wells AW, Llewellyn CA, Casbard A, Johnson AJ, Amin M, Ballard S, et al. The EASTR Study: Indications for transfusion and estimates of transfusion recipient numbers in hospitals supplied by the National Blood Service. Transfus Med. 2009;19(9):315-28.
Stainsby D, Jones H, Asher D, Atterbury C, Boncinelli A, Brant L, et al. Serious hazards of transfusion: A decade of hemovigilance in the UK. Transfus Med Rev. 2006;20(4):273-82.
Hill SR, Carless PA, Henry DA, Carson JL, Hebert PC, McClelland DBL, et al. Umbrales de transfusión y otras estrategias para determinar la transfusión de eritrocitos alogénicos. Biblioteca Cochrane Plus. [Internet] 2008 [citado 5 Abr 2011];(4). Disponible en: http://www.updatesoftware.com/BCP/BCPGetDocument.asp?DocumentID=CD002042
Klein HG, Spahn DR, Carson JL. Red blood cell transfusion in clinical practice. Lancet. 2007;370(9585):415–26.
Taylor RW, O’Brien J, Trottier SJ, Manganaro L, Cytron M, Lesko MF, et al. Red blood cell transfusions and nosocomial infections in critically ill patients. Crit Care Med. 2006;34(9):2302–8.
Heming N, Montravers P, Lasocki S. Iron deficiency in critically ill patients: highlighting the role of hepcidin. Crit Care. 2011;15(2):210.
10.Chant C, Wilson G, Friedrich FO. Anemia, transfusion, and phlebotomy practices in critically ill patients with prolonged ICU length of stay: a cohort study. Crit Care. 2006;10(5):140.
11.Corwin HL, Gettinger A, Pearl RG, et al. The CRIT study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States. Crit Care Med. 2004;32(1):39-52.
12.Hébert PC, Van der Linden P, Biro G, Hu LQ. Physiologic aspects of anemia. Crit Care Clin. 2004;20(2):187-212.
13.Morisaki H, Sibbald WJ. Tissue oxygen delivery and the microcirculation. Crit Care Clin. 2004;20(2):213-23.
14.Carless PA, Henry DA, Moxey AJ, et al. Cell salvage for minimizing perioperative allogeneic blood transfusion. Cochrane Library. 2010;(3). http://www.thecochranelibrary.com/userfiles/ccoch/file/CD001888.pdf
15.Vincent JL, Piagnerelli M. Transfusion in the intensive care unit. Crit Care Med. 2006; 34(Suppl. 5):96–101.
16.Young PP, Cotton BA, Goodnough LT. Massive transfusion protocols for patients with substantial hemorrhage. Transfus Med Rev. 2011;25(4):293-303.
17.Stanworth SJ, Walsh TS, Prescott RJ, Lee RJ, Watson DM, Wyncoll D. A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time. Crit Care. 2011;15(2):108.
18.Vincent JL, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, et al. Anemia and blood transfusion in critically ill patients. JAMA. 2002;288(12):1499-507.
19.Rana R, Afessa B, Keegan MT, Whalen FX Jr, Nuttall GA, Evenson LK, et al. Evidencebased red cell transfusion in the critically ill: Quality improvement using computerized physician order entry. Crit Care Med. 2006;34(7):1892-7.
20.Sakr Y, Chierego M, Piagnerelli M, Verdant C, Dubois MJ, Koch M, et al. Microvascular response to red blood cell transfusion in patients with severe sepsis. Crit Care Med. 2007;35(7):1639–44.