2011, Number 2
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Cir Plast 2011; 21 (2)
Effectiveness of negative wound pressure therapy versus conventional treatment in the management of acute and chronic wounds in the Petroleos Mexicanos North Central Hospital
Márquez EC, Gaytán FOF, Torres TA, Sánchez MR, Figueroa HL, Gaytán FIA, Gutiérrez BG
Language: Spanish
References: 52
Page: 92-101
PDF size: 164.33 Kb.
ABSTRACT
Treatment of acute and chronic wounds is a challenge for surgeons because it implies direct association with local and systemic diseases. We hypothesized that negative wound pressure therapy is more effective, implies less duration and cost than conventional wound management. 24 patients were studied in a period of 19 months. Each group had 12 patients with wound infection, abdominal sepsis, diabetic foot, Fournier gangrene and pressure ulcers. We studied age, sex, related illnesses, microbiology, hospital duration treatment and outpatient treatment, number and duration of surgical debridement, number of dressing changes and total costs. We used the SPSS program for Windows
® for statistical analysis. The conventional therapy group had younger patients. Males were predominant in both groups. Staphylococcus aureus was predominant in the conventional therapy group while in the negative wound pressure therapy it was Staphylococcus epidermidis. Diabetes mellitus and high blood hypertension were found in both groups. Hospital treatment was longer in the negative wound pressure therapy group. Outpatient treatment was longer in the conventional therapy group. The number and duration of surgical debridement was less in the negative wound pressure therapy, as well as wound dressings changes were fewer in the negative wound pressure therapy. Granulation tissue appeared earlier in the negative wound pressure therapy. Cost of surgical debridement was lower in the negative wound pressure therapy group. Outpatient and total cost were lower in the negative wound pressure therapy group. The negative wound pressure therapy is cost-effective and results in a reduction in the duration of the treatment of patients with acute and chronic wounds.
REFERENCES
Bouza AC, Sanz de Leon OM, Amate BJM. Effectiveness of special dressings in the treatment of pressure and leg ulcers. AETS 2001; 10: 9-103.
Fonder MA, Lazarus GS, Cowan DA, Aronson-Cook B, Kohli AR, Mamelak AJ. Treating the chronic wound: A practical approach to the care of non healing wounds and wound care dressings. J Am Acad Dermatol 2008; 58(2):185-206.
Schultz GS, Sibbald RG, Falanga V, Ayello E, Dowsett C, Harding K et al. International advisory board in wound bed preparation 2003. Wound Rep Regen 2003; 11: 1-28.
Fleischmann W, Strecker W, Bombelli M, Kinz L. Vacuum sealing as a treatment of soft tissue damage in open fractures. Unfallchirurg 1993; 96(9): 488-926.
Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg 1997; 38(6): 563-77.
Argenta A, Webb K, Simpson J, Gordon S, Kortesis B, Wanner M et al. Deformation of superficial and deep abdominal tissues with application of a controlled vacuum. European tissue repair society, focus group meeting topical negative pressure (TNP) Therapy, 4-6, 2003, London.
Venturi ML, Attinger CE, Mesbahi AN, Hess CL, Graw KS. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: A review. Am J Clin Dermatol 2005; 6: 185-94.
Saxena V, Hwang CW, Huang S, Eichbaum Q, Ingber D, Orgill DP. Vacuum-Assisted Closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg 2004; 114(5): 1086-96.
Webb LX. New techniques in wound management: Vacuum-assisted wound closure. J Am Acad Orthop Surg 2002; 10: 303.
Clare MP, Fitzgibbons TC, McMullen ST, Stice RC, Hayes DF, Henkel L. Experience with the vacuum assisted closure negative pressure Technique in the treatment of non-healing diabetic and dysvascular wounds. Foot Ankle Int 2002; 23: 896.
Price J. Surgical intervention in cases of peritonitis. Proc Philadelphia. County Med Soc 1905; 26: 92.
Venturi ML, Attinger CE, Mesbahi AN, Hess CL, Graw KS. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: a review. Am J Clin Dermatol 2005; 6: 185-94.
Greene A, Puder M, Roy R, Arsenault D, Kwei S, Moses M et al. Microdeformational wound therapy, effects on angiogenesis and matrix metalloproteinases in chronic wounds of 3 debilitated patients. Ann Plast Surg 2006; 56: 418-422.
Saxena V et al. Vacuum-assisted closure: Microdeformations of wounds and cell proliferation. Plast Reconstr Surg 2004; 114(5): 1086-1096.
Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: Part II. The influence of the rate and frequency of distraction. Clin Orthop 1989; 239: 263.
Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop 1989; 238: 249.
Harvey EJ, Grujic L, Early JS, Benirschke SK, Sangeorzan BJ. Morbidity associated with ORIF of intra-articular calcaneus fractures using a lateral approach. Foot Ankle Int 2001; 22: 868-873.
Webb LX. New techniques in wound management: vacuum-assisted wound closure. J Am Acad Orthop Surg 2002; 10: 303-311.
Robledo-Ogazón F, Mier y Díaz J, Sánchez-Fernández P, Suárez-Moreno R, Vargas-Rivas A, Bojalil-Durán L. Uso del sistema de cierre asistido al vacío VAC en el tratamiento de las heridas quirúrgicas infectadas. Experiencia Clínica. Cir Ciruj 2006; 74: 107-113.
Fabian TS, Kaufman HJ, Lett ED, Thomas JB, Rawl DK, Lewis PL. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full thickness wound healing. Am Surg 2000; 66: 1136-1143.
Genecov DG, Schneider AM, Morykwas MJ, Parker D, White WWL, Argenta LC. A controlled sub-atmospheric pressure dressing increases the rate of skin graft donor site reepithelialization. Ann Plast Surg 1998; 40: 219-225.
Morykwas MJ, Faler BJ, Pearce DJ, Argenta LC. Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine. Ann Plast Surg 2001; 47: 547–551.
Morykwas MJ, Howell H, Bleyer AJ, Molnar JA, Argenta LC. The effect of externally applied subatmospheric pressure on serum myoglobin levels after a prolonged crush/ischemia injury. J Trauma 2002; 53: 537-540.
De la Torre JI, Martin SA, Oberheu AM, Vasconez LO. Healing a wound with an exposed Herrington rod: A case study. Ostomy Wound Manag 2002; 48: 18-19.
De Lange MY, Schasfoort RA, Obdeijn MC, van der Werff JFA, Nicolai JPA. Vacuum-assisted closure: indications and clinical experience. Eur J Plast Surg 2000; 23: 178–182.
Genecov DG, Schneider AM, Morykwas MJ, Parker D, White WWL, Argenta LC. A controlled sub-atmospheric pressure dressing increases the rate of skin graft donor site reepithelialization. Ann Plast Surg 1998; 40(3): 219-225.
Shirakawa M, Isseroff RR. Topical negative pressure devices: use for enhancement of healing chronic wounds. Arch Dermatol 2005; 141: 1449-53.
Venturi ML, Attinger CE, Mesbahi AN, Hess CL, Graw KS. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: a review. Am J Clin Dermatol 2005; 6: 185-94.
DeFranzo AJ, Argenta LC, Marks MW, Molnar JA, David LR, Webb LX et al. The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone. Plast Reconstr Surg 2001; 108(5): 1184-91.
Gustafsson R, Johnsson P, Algotsson L, Blomquist S, Ingemansson R. Vacuum-assisted closure therapy guided by C-reactive protein level in patients with deep sternal wound infection. J Thorac Cardiovasc Surg 2002; 123: 210–215.
Heugel JR, Parks KS, Christie SS, Pulito JR, Zegzula DH, Kamalyan NA. Treatment of the exposed Achilles tendon using negative pressure wound therapy: a case report. J Burn Care Rehabil 2002; 23: 167–171.
Greer S, Sims CD, Borud L, Thorne C, Kasabian A. The use of a subatmospheric pressure dressing to salvage a septic ankle with concomitant osteomyelitis and avert a free flap. Nursing Standard 1997; 11: 151–156.
Mullner T, Mrkonjic L, Kwasny O, Vecsei V. The use of negative pressure to promote the healing of tissue defects: a clinical trial using the vacuum sealing technique. Br J Plast Surg 1997; 50: 194-9.
Gwan-Nulla DN, Casal RS. Toxic shock syndrome associated with the use of the vacuum assisted closure device. Ann Plast Surg 2001; 47: 552-4.
Czymek R, Schmidt A, Eckmann C, Bouchard R, Wulff B, Laubert T et al. Fournier’s gangrene: vacuum-assisted closure versus conventional dressings. Am J Surg 2009; 197: 168-176.
Durmish Y, Gervaz P, Buhler L, Bucher P, Zufferey G, Al-Mazrouei A et al. Vacuum-assisted abdominal closure: its role in the treatment of complex abdominal and perineal wounds. Experience in 48 patients. J Chir 2007; 144(5): 464-6.
Stainier A. Fournier’s gangrene on ischial pressure ulcer: use of vacuum-assisted closure and therapeutic strategy. Prog Urol 2007; 17(5): 1000-2.
Andersen CA, Roukis TS. The Diabetic Foot. Sur Clin N Am 2007; 87: 1149-1177.
Roukis TS. Radical solutions: bold debridement techniques can work for both chronic and acute wounds. OrthoKinetic Rev 2004; 4(1): 20-23.
Apelqvist J, Armstrong DG, Lavery LA, Boulton AJ. Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds. Am J Surg 2008; 195: 782-788.
Armstrong DG, Lavery LA, Abu-Rumman P, Espensen EH, Vazquez JR. Nixon BP et al. Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot. Ostomy Wound Manage 2002; 48: 64.
Armstrong DG, Attinger CE, Boulton AJM. Frykberg RG, Kirsner RS, Lavery LA et al. Guidelines regarding negative wound therapy (NPWT) in the diabetic foot. Ostomy Wound Manage 2004; 50 (Suppl 4B): 3S–27S.
Hersh RE, Jack JM, Dahman MI, Morgan RF, Drake DB. The vacuum-assisted Closure device as a bridge to sternal wound closure. Ann Plast Surg 2001; 46: 250-4.
Edmonds M, Bates M, Doxford M, Gough A, Foster A. New treatments in ulcer healing and wound infection. Diabetes Metab Res Rev 2000; 16(Suppl 1): S51-4.
Armstrong DG, Lavery LA. Negative pressure wound after partial diabetic foot amputation: a multicentre, randomized controlled trial. Lancet 2005; 366: 1704-10.
Cro C, George KJ, Donnely J, Irwin ST, Gardiner KR. Vacuum assisted closure system in the management of enterocutaneous fistulae. Postgrad Med J 2002; 78: 364-365.
Medeiros AC, Aires-Neto T, Marchini JS, Brandão-Neto J, Valença DM, Egito EST. Treatment of postoperative enterocutaneous fistulas by high-pressure vacuum with a normal oral diet. Dig Surg 2004; 21: 401-405.
Erdman D, Drye C, Heller L, Wong M, Levin S. Abdominal wall defect and enterocutaneous fistula treatment with the Vacuum-Assisted Closure (VAC) system. Plast Reconstr Surg 2001; 108: 2066-2068.
Denzinger S, Luebke L, Burger M, Kessler S, Wieland WF, Otto W. Vacuum-assisted closure therapy in ureteroileal anastomotic leakage after surgical therapy of bladder cancer. World J Surg Oncol 2007; 5: 41.
Ramírez JM, Becerril PM, Sánchez MR, Márquez EC, Torres TA, Legorreta CC. Sistema de presión negativa en el manejo del abdomen abierto por sepsis. Rev Asoc Mex Med Crít Ter Int 2007; 2: 74-91.
Moues CM, Van den Bemd GJ, Meerding WJ, Hovius SE. An economic evaluation of the use of TNP on full-thickness wounds. J Wound Care 2005; 14: 224-7.
Braakenburg A, Obdeijn MC, Feitz R, Van Rooij IALM, Van Griethuysen AJ. Klinkenbijl JHG. The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial. Plast Reconstr Surg 2006; 118: 390-7.