2011, Number 2
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Arch Neurocien 2011; 16 (2)
Clinical and demographic features of Parkinson’s disease from a tertiary referral center
Rodríguez-Violante M, Villar-Velarde A, Valencia-Ramos C, Cervantes-Arriaga A
Language: Spanish
References: 20
Page: 64-68
PDF size: 152.64 Kb.
ABSTRACT
Parkinson’s disease is one of the most frequent neurodegenerative disorders. Mexico currently lacks reliable epidemiological studies regarding this disease.
Objective: to describe the prevalence and associations of the demographic, clinical and theraputhic features of Parkinson’s disease patients attending to the National Institute of Neurology and Neurosurgey in Mexico City in order to assess external validity.
Patients and methods: we conducted an analytic cross-sectional study of all cases seen at the Abnormal Movement betwewn june 2007 and july 2009.
Results: a total of 402 clinical files were reviewed from which 212 corresponded to Parkinson’s disease. Mean age was 63.1±11.4 years, 93% had mild to moderate disease, 70% were on levodopa preparations and 95% has at least one non-motor dysfunction symptom. Mean age of disease onset was around 3 years lower compared to other studies with men having an earlier onset (54.5 vs 59.9 years).
Conclusions: with the only exception of age of disease onset, all other features of our hospital-based population are similar and therefore comparable with international population-based studies. Since actual epidemiologic data of Parkinson’s disease in Mexico is still missing this study may provide a broad picture of the current state of the disease in the country.
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