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Colegio de Medicos y Cirujanos República de Costa Rica

2011, Number 599

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Rev Med Cos Cen 2011; 68 (599)

Esclerosis múltiple de inicio tardío

Mora RC, Fernández MH, Alvarado CF

Language: Spanish
References: 17
Page: 467-474
PDF size: 617.62 Kb.


ABSTRACT

Multiple Sclerosis, demyelinating, inflammatory, slowly progressing disease, presents itself as low onset (in patients older than 50 years of age) in 6 to 7% of the cases, although its prevalence may relate to little or no suspicion of the disease. The primary progressive form predominates and the symptomatology of onset is predominantly of motor compromise, and we observe less brevity between the first and the second crisis and the beginning of the progressive disease. In the diagnosis, The MRI lesions are less enhanced to Gd and the oligoclonal bands have less sensitivity. The CNS biopsy has great importance in the diagnosis of clinical syndromes in which we find no clear cause. In the differential diagnosis we need to discard in first place cerebrovascular disease and neoplasia (especially CNS lymphoma).


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