2011, Number 07-08
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Medicina & Laboratorio 2011; 17 (07-08)
Hepatitis B
Toro MAI, Restrepo GJC
Language: Spanish
References: 56
Page: 311-329
PDF size: 1249.82 Kb.
ABSTRACT
Hepatitis B virus is a common viral pathogen that chronically infects almost 400 million people worldwide, who have a permanent risk of developing cirrhosis and/or hepatocellular carcinoma. The natural history of hepatitis B virus infection is dynamic, and patients can fluctuate between periods of active liver inflammation and periods of inactive disease. Disease progression is influenced by various factors, including viral genotype, age at the time of infection, and male gender, among others. Persons with high risk of infection by hepatitis B virus should be serologically evaluated and if found negative, should be vaccinated; if found positive, they should be monitored until a chronic infection is ruled out. If chronic infection is developed, patients should be monitored for life to try to control the appearance of cirrhosis, or even worst, hepatocellular carcinoma.
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