Pyke MA, Zemelman A, Chiovino L, García BML, Madeo MC, Sánchez G, Merola G

Language: Spanish
References: 13
Page: 260-263
PDF size: 527.51 Kb.

ABSTRACT

A paraguayan male patient, with nodular, tumor, warty and scarring lesions in the left leg that had evolved over a period of 20 years is reported. With the inicial diagnosis of a deep fungal infection, complementary testing confirmed the diagnosis of chromoblastomycosis caused by Fonsecae pedrosoi. While combination therapy is still being described as first line treatment, in this case we observed an excellent response to itraconazole as monotherapy.

REFERENCES

1. Manzur ME, Canonici L, Monteros MH, Morichell IM. Cromomicosis. A propósito de dos casos. Arch Argent Dermatol 2005; 55: 245-9.

2. Schwartz R, Baran E. Chromoblastymycosis. [en línea] Medscape´s continually updated clinical references. Last update 2010 jul 8 ‹ http://emedicine.medscape.com/article/1092695-overview> [fecha de consulta 18 de septiembre de 2010].

3. Solalinde L, Di Martino B, Rodriguez Masi M, Knopfelmacher O, Bolla de Lezcano L. Tratamiento de la cromomicosis bilateral con pulsos de itraconazol. Act Terap Dermatol 2008; 31: 44-4.

4. Arenas R. Micología Médica Ilustrada. Segunda edición. Edit. McGraw-Hill. Septiembre 2004.

5. Park SG, Oh SH, Suh SB, Lee KH, Chung KY. A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: treatment with a combination of amphotericin B and 5-flucytosine. Br J Dermatol 2005; 152: 560-4.

6. De los Ríos EH, Alperovich BA, Anzorena JA, Lorenz AM, De los Ríos R. Tratamiento médicoquirúrgico de la cromomicosis. Act Terap Dermatol 1997; 20: 21-6.

7. Menezes N, Varela P, Furtado A, Cruceiro A, Calheiros I, Rosado L et al. Chromoblastomycosis associated with Fonsecaea Pedrosoi in a carpenter handling exotic woods. DOJ 2008; 14: 9.

8. Negroni R, Arechavala A, Maiolo E, Bianchi M, Santiso G, Garro S, Orduna T. Clinical cases in medical mycology. Case nº 31. Rev Iberoam Micol 2008; 25: 62-4.

9. Torres Rodriguez JM et al. Micología médica. Editorial Masson, 1993.

10. Estrada-Chavez G, Arenas R, Vega-Memije E, Bonifaz A. Cromoblastomicosis. Un caso por Fonsecaea pedrosoi con filamentación in vivo y tratamiento combinado con itraconazol y criocirugía. Dermatol Cosm Med Quir 2003; 1: 40-3.

11. Negroni R. Tratamiento actual de las micosis subcutáneas. Dermatol Arg 1999; 5: 253-6.

12. Negroni R, Tobón A, Bustamante B, Shikanai- Yasuda MA, Patino H, Restrepo A. Posaconazole treatment of refractory eumycetoma and chromoblastomycosis. Rev Inst Med Trop Sao Paulo 2005; 47: 339-6.

13. Alió A, Castro S, Mendoza M, Hernández I, Diaz E, Cavallera E et al. Cromomicosis: uso del tratamiento combinado de itraconazol y 5-fluorouracilo en Fonsecae pedrosoi e itraconazol y criospray en Exophiala jeanselmei var. Lecanii-corni. Derm Venez 2001; 39: 11-5.