Castañeda SF, Galindo RF, Gutiérrez GVM

Language: Spanish
References: 21
Page: 105-110
PDF size: 53.91 Kb.

ABSTRACT

Introduction: Hirschsprung’s disease (HD) is considered a congenital entity characterized by an absence of ganglion cells in the myenteric plexus of Auerbach and Meissner in the submucosa of the rectum and colon in other segments of the ascending (from tail o head). This alteration causes an abnormality of intestinal motility, which most frequently manifest as an intestinal obstruction. Objective: To determine the clinical and epidemiological characteristics of children with Hirschsprung’s disease at the Hospital for Children of IMIEM in the period from January 1, 2007 to December 31, 2010. Material and methods: We accessed the pathology service for Hospital for Children where they were collected biopsy results made to patients with suspected HD from 2007 to 2010 to be the results, was investigated in the file through the hospital clinical records, clinical characteristics of patients, focusing especially on clinical history. Results: The study revealed 21 patients with HD confirmed by biopsy, 18 men and three women, 10 patients younger than one year and 11 between two and 15 years. Three of the 21 patients were overweight, three were eutrofics and the remaining 15 had some degree of malnutrition. 70% of patients had symptoms in the first year of age. The main symptom was abdominal distension and constipation second. Of the patients studied, 17 had long-segment disease, three short segments, an one ultrashort segment. 70% of patients had the disease in isolation. 100% of the patients were diagnosed by biopsy. Until the study 10 patients had been treated surgically by declining Duhamel, one Rehbein’s surgery and 10 are awaiting surgical correction. Conclusions: It should be emphasized especially in the diagnosis and several patients biopsied ganglion cells present, but also have clinical HD, these patients may be part of Hirschsprung’s syndrome and may require more specific diagnostic techniques such as staining acetylcholinesterase, which would help us to confirm the diagnosis of more patients and having specificity 100%, this would be cause for further research.

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