Valencia VEY, Canto CT, López HLB, Coral VRM, Canto CP

Language: Spanish
References: 47
Page: 163-168
PDF size: 246.28 Kb.

ABSTRACT

Preeclampsia, a common complication of pregnancy, is characterized by elevated blood pressure and proteinuria developing after 20 weeks of gestation, in which the etiological components may vary in different populations. Susceptibility to preeclampsia is believed to have a genetic component, as several studies have reported associations between polymorphisms of different genes such as MTHFR, AGT, ACE, GSTP1, eNOS, TNF-α, IL-6, and others. However, most of the studies have been performed on populations of European and Asian ancestry with varying results; this suggests a possible relationship between polymorphisms and ethnic groups in the different populations studied. The aim of this review is to show the role of the genetics factors in preeclampsia, as well as studies performed in Mexican-Mestizo women with this syndrome.

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