Contreras CNA, Robles-Landa LPA

Language: Spanish
References: 10
Page: 99-108
PDF size: 96.42 Kb.

ABSTRACT

Heparin-associated thrombocytopenia (HAT) occurs in 5-10% of patients treated with heparin and has two forms of presentation: the severe form is caused by the presence of heparin-dependent antibodies that produce platelet aggregation and possible thrombosis. HAT with thrombosis is rare (0.2-0.4%) but worsens the prognosis and may entail immediate discontinuation of heparin administration, treatment of complications, and the use of alternative therapy for anticoagulation. Its diagnosis is based on clinical criteria and may be supported by laboratory tests for heparin-dependent antibodies.

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