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2004, Número 2

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Med Sur 2004; 11 (2)


Papel fisiológico del factor de crecimiento similar a la insulina tipo 1 y sus proteínas ransportadoras durante el embarazo

Díaz DE, Pichardo-Bahena R, Larrea GF, Halhali BA

Idioma: Español
Referencias bibliográficas: 57
Paginas: 57
Archivo PDF: 104.21 Kb.


RESUMEN

El factor de crecimiento similar a la insulina tipo I (IGF-I) y sus proteínas transportadoras (IGFBPs), desempeñan un papel importante en la regulación del crecimiento fetal. Estos factores proteínicos son producidos virtualmente por todos los órganos fetales desde el desarrollo temprano y son potentes estimuladores de la división y la diferenciación celular. Esta revisión está encaminada a discutir algunos aspectos generales del papel fisiológico del IGF-I y sus IGFBPs durante el embarazo, la regulación de las acciones biológicas del IGF-I por sus IGFBPs y las alteraciones de estos factores durante el retraso del crecimiento intrauterino y la preeclampsia.


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