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ISSN 0210-5187 (Electronic)

2011, Number 3

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Med Cutan Iber Lat Am 2011; 39 (3)

Dermatosis in patients with end-stage chronic renal failure on peritoneal dialysis

Fernández SM, Orozco TR, Correa RR, Villa A

Language: Spanish
References: 28
Page: 106-111
PDF size: 1894.07 Kb.


ABSTRACT

The treatment of patients with final renal disease (FRD) includes dialysis and renal transplant. Skin and nails can show different changes related to the renal failure and the dialysis method. The objective of this study is to describe the skin involvement of the patients with FRD in peritoneal dialysis.
Methods: Patients with FRD in peritoneal dialysis were included. Univariable and multivariable analysis were performed to describe the relationship between some of the dermatosis and important clinical and laboratory tests variables.
Results: Eighty six patients were included: 37 women and 49 men. The 70.9% were on continuous ambulatory peritoneal dialysis; 68 patients had pruritus, 54 xerosis and 58 ungueal involvement. Pruritus was related to anemia (p = 0.018) and immunosupressors drug use (p = 0.032). Xerosis was related to ungueal involvement (p = 0.008), excoriations (p = 0.024) and hyperglycemia (p = 0.015). Continuous ambulatory peritoneal dialysis was a protector factor for hyperpigmentation (p = 0.033) as well as antacids drugs use (p = 0.016) and hyperuricemia (p = 0.048). The age was a protector factor for the presence of ungueal Beau´s lines (p = 0.007) and statins drugs use had a risk factor for the same variable (p = 0.002). Ungueal pallor was related to the FRD etiology (p = 0.049). Eritropoyetin use and phosphorus serum levels were found as protector factors for ungueal pallor (p = 0.042 and p = 0.047, respectively).
Conclusions: Incidence of dermatosis asociated with ESRD and peritoneal dialysis in mexican patients is similar to that published in the world literature. It is important to diagnose and treat such dermatosis in order to improve the quality of life of affected patients.We propose to review these results in order to establish whether this association exists or is coincidental.


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