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2011, Number 5

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Salud Mental 2011; 34 (5)

Estructura del sueño y funciones ejecutivas en niños con depresión

Moo EJA, Valencia FM, Ulloa FRE, Ostrosky SF, Reyes LI

Language: Spanish
References: 57
Page: 459-468
PDF size: 114.54 Kb.


ABSTRACT

Sleep disturbance is a common complaint in depression. However, objective data in relation to the architecture of sleep associated with depression in childhood have been inconsistent. The objective measurement of sleepiness and executive functions is little known in depressive children. The objective of this study was to determine the differences in the sleep architecture, daytime sleepiness and executive functions in children with and without depression.
Method: The participants were 20 children with an average of 10.5 (SD=1.5) years old; nine were girls. Ten met the diagnostic criteria for major depression and ten were control. There were no differences by sex and age between groups with and without depression (p›.05). The instruments were: Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL), the Children Depression Inventory, and the Battery of Executive Frontal Functions. Also, there were two consecutive nights of polysomnographic recording and Multiple Sleep Latency Test (MSLT).
Results: No differences were found in the architecture of sleep, sleep efficiency was greater than 90% in both groups and the indexes of initiation and sleep maintenance did not show statistically significant differences. There were no differences in daytime sleepiness, sleep onset latency in the MSLT was 22.8 (SD=6.4) minutes for the group with depression and 23.7 (SD=4.1) for the control. The executive functions showed differences in tasks involving: visual-motor and impulse control, working memory and identification of the riskbenefit ratio.
Conclusions: The results suggest that prefrontal structures are more vulnerable to depression than the structures that regulate the circadian and homeostatic sleep.


REFERENCES

  1. Ivanenko A, Crabtree VM, Obrien LM, Gozal D. Sleep complaints and psychiatric symptoms in children evaluated at a pediatric mental health clinic. J Clin Sleep Med 2006;15(1):42-48.

  2. Lofthouse N, Gilchrist R, Splaingard M. Mood-related sleep problems in children and adolescents. Child Adolesc Psychiatr Clin N Am 2009;18(4):893-916.

  3. Bertocci MA, Dahl RE, Williamson, DE, Iosif AM et al. Subjective sleep complaints in pediatric depression: A controlled study and comparison with EEG measures of sleep and waking. J Am Acad Child Adolesc Psychiatry 2005;44:1158-1166.

  4. Liu X, Buysse DJ, Gentzler AL, Kiss E et al. Insomnia and hypersomnia associated with depressive phenomenology and comorbidity in childhood depression. Sleep 2007;30:83–90.

  5. Lofthouse N, Fristad M, Splaingard M, Kelleher K. Child reports of sleep problems associated with early-onset bipolar spectrum disorders. J Family Therapy 2007;1:114-123.

  6. Rao U, Dahl RE, Ryan ND, Birmaher B et al. Heterogeneity in EEG sleep findings in adolescent depression: unipolar versus bipolar clinical course. J Affective Disorders 2002;70:273–280.

  7. Rao U, Chen LA. Characteristics, correlates, and outcomes of childhood and adolescent depressive disorders. Dialogues Clin Neurosci 2009;11:45–62.

  8. Ivanenko A, Johnson K. Sleep disturbances in children with psychiatric disorders. Seminars Pediatric Neurology 2008;15:70-78.

  9. Forbes E, Michele A. Bertocci M, Alice M et al. Objective sleep in pediatric anxiety disorders and major depressive disorder. J Am Acad Child Adolesc Psychiatry 2008;47:148–155.

  10. Arana-Lechuga Y, Núñez-Ortiz R, Terán-Pérez G, Castillo-Montoya C et al. Sleep-EEG patterns of school children suffering from symptoms of depression compared to healthy controls. World J Biol Psychiatry 2008;9: 115-120.

  11. Emslie GJ, Armitage R, Weinberg WA, Rush AJ et al. Sleep polysomnography as a predictor of recurrence in children and adolescents with major depressive disorder. Int J Neuropsychopharmacol 2001;4:159-168.

  12. American Academy of Sleep Medicine. The international classification of sleep disorders, diagnostic and coding manual. Segunda edición. Westchester: American Academy of Sleep Medicine; 2005.

  13. Armitage R, Hoffmann R. Sleep electrophysiology of major depressive disorders. Current Review Mood Anxiety Disorders 1997;1:139-151.

  14. Benca R, Obermeyer W, Thisted R, Gillin C. Sleep and psychiatric disorders: A meta-analysis. Arch Gen Psychiatry 1992;49:651-668.

  15. Kotagal S. Hypersomnia in children: interface with psychiatric disorders. Child Adolesc Psychiatr Clin N Am 2009;18(4):967-977.

  16. Reséndiz M, Valencia Flores M, Santiago V, Castaño V et al. Somnolencia diurna excesiva: causas y medición. Rev Mex Neuroci 2004;5:147-155.

  17. Velten-Schurian K, Hautzinger M, Poets CF, Schlarb AA. Association between sleep patterns and daytime functioning in children with insomnia: the contribution of parent-reported frequency of night waking and wake time after sleep onset. Sleep Med 2010;11(3):281-288.

  18. Calhoun SL, Vgontzas AN, Fernandez-Mendoza J, Mayes SD et al. Prevalence and risk factors of excessive daytime sleepiness in a community sample of young children: the role of obesity, asthma, anxiety/depression, and sleep. Sleep 2011;34:503-507.

  19. Moo Estrella JA, Pérez Benítez H, Solís-Rodríguez F, Arankowsky-Sandoval G. Evaluation of depressive symptoms and sleep alterations in college students. Arch Medical Research 2005;36:393-398.

  20. Mume CO. Excessive daytime sleepiness among depressed patients. Libyan J Med 2010;5:4626-doi:10.4176/091024.

  21. Laxhmi-Chellappa´ S, Fontenele Araújo J. Excessive daytime sleepiness in patients with depressive disorder. Rev Bras Psiquiatr 2006 28(2):126-129.

  22. Jiménez Genchi A, Flores Flores G, Zavaleta Ramírez P, Nenclares Portocarrero A. Evaluación de la somnolencia en pacientes deprimidos empleando la Escala de Somnolencia de Epworth. PSIQUIS 2008;17(6):182-190.

  23. Fava M. Daytime sleepiness and insomnia as correlates of depression. J Clin Psychiatry 2004;65:27-32.

  24. Zalsman G, Oquendo MA, Greenhill L, Goldberg PH et al. Neurobiology of depression in children and adolescents. Child Adolesc Psychiatr Clin N Am 2006;15:843-868.

  25. Caetano SC, Fonseca M, Hatch JP, Olvera RL et al. Medial temporal lobe abnormalities in pediatric unipolar depression. Neurosci Lett 2007;427: 142-147.

  26. DelBello MP, Adler CM, Strakowski SM. The neurophysiology of childhood and adolescent bipolar disorder. CNS Spectr 2006;11:298-311.

  27. Serene JA, Ashtari M, Szeszko PR, Kumra S. Neuroimaging studies of children with serious emotional disturbances: a selective review. Can J Psychiatry. 2007;52:135-145.

  28. Scheuerecker J, Frodl T, Koutsouleris N, Zetzsche T et al. Cerebral differences in explicit and implicit emotional processing and fMRI study. Neuropsychobiology 2007;56:32-39.

  29. Forbes EE, May CJ, Siegle GJ, Ladouceur CD et al. Reward-related decision- making in pediatric major depressive disorder: an fMRI study. J Child Psychol Psychiatry 2006;47:1031-1040.

  30. Pavuluri MN, O’Connor MM, Harral E, Sweeney JA. Affective neural circuitry during facial emotion processing in pediatric bipolar disorder. Biol Psychiatry 2007;62:158-167.

  31. Leibenluft E, Rich BA, Vinton DT, Nelson EE et al. Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder. Am J Psychiatry 2007;164:52-60.

  32. Andrew SD. The neuropsychological basis of childhood psychopathology. Psychology in the Schools 2006;43:503-513.

  33. Fossati P, Ergis AM, Allilaire JF. Executive functioning in unipolar depression: a review. Encephale 2002;28:97-107.

  34. American Psychiatric Association. Diagnostic criteria from DSM-IV-TR. Washington; 2000.

  35. Kovacs M. Inventario de depresión infantil (CDI). Madrid: TEA Ediciones; 2004.

  36. Kaufman J, Birmaher B, Brent D, Rao U et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 1997;36:980-988.

  37. Ulloa RE, Ortiz S, Higuera F, Nogales I et al. Estudio de fiabilidad interevaluador de la versión en español de la entrevista Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL). Actas Esp Psiquiatr 2006;34:36-40.

  38. Flores J, Ostrosky-Solís F. Batería de funciones frontales y ejecutivas. Rev Neuropsicología, Neuropsiquiatría Neurociencias 2008;8:141-158.

  39. American Academy of Sleep Medicine. The AASM Manual for the scoring of sleep and associated events: Rules, terminology and technical specifications. Westchester: Autor; 2007.

  40. Jasper HH. The 10–20 electrode system of the international federation. Electroencephalogr Clin Neurophysiol 1958;10:370–375.

  41. Moo Estrella JA, Castaño Meneses A, Gil Aldeco D, Rodríguez Pérez V et al. Los hábitos y problemas relacionados con el dormir como factores de riesgo para la depresión infantil. Congreso Nacional para la Investigación y Medicina del Sueño, Jalisco. Veracruz; 2009.

  42. Terzano MG, Parrino L, Smerieri A et al. Atlas, rules, and recording techniques for the scoring of cyclic alternating pattern (CAP) in human sleep. Sleep Med 2002;3:187-199.

  43. Lopez J, Hoffmann R, Armitage R. Reduced sleep spindle activity in early-onset and elevated risk for depression. J Am Acad Child Adolesc Psychiatry 2010;49:934-943.

  44. Brody AL, Saxena S, Mandelkern MA, Fairbanks LA et al. Brain metabolic changes associated with symptom factor improvement in major depressive disorder. Biol Psychiatry 2001;50:171–178.

  45. Drevets WC, Price JL, Furey ML. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct 2008;213(1-2):93–118.

  46. Gillin JC, Sitaram N, Duncan WC. Muscarinic supersensitivity:a possible model for the sleep disturbance of primary depression? Psychiatry Res 1979;1:17–22.

  47. Sadek N, Nemeroff C. Actualización en neurobiología de la depresión. Revista Psiquiatría Uruguay 2000;64:462-485.

  48. Ginicola MM. Children’s unique experience of depression: Using a developmental approach to predict variation in symptomatology. Child Adolescent Psychiatry Mental Health 2007;1:9-doi:10.1186/1753-2000-1-9.

  49. Kerr J, Beer J. Specific and diversive curiosity and depression in junior high school students of divorced and nondivorced parents. Psychol Rep 1992;71:227-231.

  50. Gass CS, Ansley J, Boyette S. Emotional correlates of fluency test and maze performance. J Clinical Psychology 1994;50(4):586-590.

  51. Smoski MJ, Lynch TR, Rosenthal MZ, Cheavens JS et al. Decision-making and risk aversion among depressive adults. J Behav Ther Exp Psychiatry 2008;39(4):567-576.

  52. Garon N, Moore C, Waschbusch DA. Decision making in children with ADHD only, ADHD-anxious/depressed, and control children using a child version of the Iowa Gambling Task. J Atten Disord 2006;9:607-619.

  53. Elliott R, Sahakian BJ, Michael A, Paykel ES et al. Abnormal neural response to feedback on planning and guessing tasks in patients with unipolar depression. Psychological Medicine 1998;28:559-571.

  54. Zelazo PD, Craik FIM, Booth L. Executive function across the life span. Acta Psychologica 2005;115:167–183.

  55. Huang W, Ramsey KM, Marcheva B, Bass J. Circadian rhythms, sleep, and metabolism. J Clin Invest 2011;121:2133-2141.

  56. Franken P, Dijk DJ. Circadian clock genes and sleep homeostasis. Eur J Neurosci 2009;29:1820-1829.

  57. Geiger A, Achermann P, Jenni OG. Association between sleep duration and intelligence scores in healthy children. Dev Psychol 2010;46:949-954.




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