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Patología Revista Latinoamericana

2011, Number 3

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Patol Rev Latinoam 2011; 49 (3)

Dysembrioplastic neuroepithelial tumor: experience in material of biopsies from three pediatric hospitals

Rodríguez VA, Perezpeña DM, Ridaura SC

Language: Spanish
References: 40
Page: 210-216
PDF size: 245.68 Kb.


ABSTRACT

Background: Tumors of the central nervous system are the main cancer-related cause of mortality in children. The purpose of this work is to present the experience on dysembryoplastic neuroepithelial tumour (DNET) in a group of children from three pediatric reference hospitals in Mexico City.
Materials and methods: This is a prospective, descriptive, retrospective study. Files from the Pathology Departments of Hospital de Pediatria del Centro Medico Nacional Siglo XXI, Hospital Infantil de Mexico Federico Gomez and Instituto Nacional de Pediatria were reviewed in a 6, 10 and 13 years respectively. Relevant clinical data were also reviewed.
Results: From 1,395 central nervous system tumors reviewed, 1.5% corresponded to DNET. Patients age average 7.6 years; slight men predominance was observed. Epileptic seizures were present in all cases, frontal and temporal lobes were the more frequent regions affected.
Conclusion: Dysembryoplastic neuroepithelial tumour is a rare neoplasia of the central nervous system; in our cases it presented in young scholar children, mainly in the frontal and temporal areas.


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