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Órgano Oficial del Hospital Angeles Health System

2011, Number 3

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Acta Med 2011; 9 (3)

Hemorrhagic necrotizing pneumonia and CA-MRSA as an emerging cause

Rojo EA, Videgaray OF, Raffoul CI

Language: Spanish
References: 59
Page: 143-148
PDF size: 86.96 Kb.


ABSTRACT

Staphylococcus aureus has been recognized as a cause of community acquired pneumonia. Methicillin resistant S. aureus (MRSA) pneumonia has been limited to hospitals, mainly with health care associated pneumonia and mechanical ventilation. In 1999, four pediatric deaths were reported necrotizing pneumonia secondary to community-acquired MRSA (CA-MRSA). These infections were caused by strains that differ from typical nosocomial strains according to their patterns of antibiotic susceptibility and pulsed field gel electrophoresis (PFGE) characteristic. In 2002, an association between the presence of Panton-Valentine leukocidin (PVL) staphylococcus toxin associated with tissue necrosis and the syndrome described previously in acute hemorrhagic necrotizing pneumonia in healthy subjects who have staphylococcal community aquired pneumonia was found. We present the case of CA-MRSA necrotizing pneumonia and review of the origins, pathophysiology, clinical features and treatment options for this emerging entity.


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