2011, Number 2
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Otorrinolaringología 2011; 56 (2)
Clinical characteristics of the new epidemic of influenza A (H1N1)
Rodríguez VM, Prado CH, Bravo EGA, Valdez VRR, Figueroa MR
Language: Spanish
References: 17
Page: 82-89
PDF size: 298.83 Kb.
ABSTRACT
Background: Influenza is a respiratory disease. In April 2009 an epidemic due to the virus of influenza A (H1N1) was described. Clinical symptoms vary from slight respiratory diseases to inferior respiratory tract diseases, dehydration or pneumonia.
Objective: To describe the clinical characteristics at the moment of the initial evaluation of patients with acute respiratory symptoms. To compare clinical characteristics of confirmed cases and cases with negative RT-PCR test.
Material and method: A retrospective study assessed the records done during the initial evaluation of patients who assisted to valuation to the General Hospital Dr. Manuel Gea Gonzalez with confirmatory test (RT-PCR) from April to September 2009.
Results: One thousand one hundred eight records of patients (mean age: 32 ± 18 years) were studied, 493 were women. Thirty-two percent of cases were confirmed. Thirty-four percent of patients who assisted to evaluation presented in the first 24 hours of the symptoms starting. The statistically significant referred symptoms were: presence or recent history of fever or myalgias and general state attack; at the physical exploration: cough, disorientation and coryza. About comorbidities, asthma was significant. Thirty percent were children; 89% of studied population had influenzalike illness, 92% of confirmed population had that syndrome and 87% of not-confirmed cases did not meet criteria for this syndrome.
Conclusions: There are significant differences in systemic symptoms, which are more frequent in the group of confirmed cases.
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Novel Swine-Origin Influenza A H1N1 Virus Investigation Team. Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans. N Eng J Med 2009;360:2605-2615.
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Zambon MC, Stockton JD, Clewley JP, Fleming DM. Contribution of influenza and respiratory syncytial virus to community cases of influenza-like illness: an observational study. Lancet 2001;358(9291):1410-1416.
Falsey AR, Treanor JJ, Betts RF, Walsh EE. Viral respiratory infections in the institutionalized elderly: clinical and epidemiologic findings. J Am Geriatr Soc 1992;40(2):115-119.