Herrera FI, Cuevas GM, Flores E, Dies SP, Valadez RMT, Romero BBL

Language: Spanish
References: 20
Page: 168-173
PDF size: 275.55 Kb.

ABSTRACT

Objective: The aim of this paper is to show the usefulness of CT for detecting early-stage optic nerve invasion in patients with retinoblastoma, based on its thickness and compared with the real thickness obtained in the histopathological studies of enucleated eyes, where the invasion was found.
Material and methods: Retrospective and longitudinal study that included patients of both sexes with ages ranging from 3 months to 11 years with confirmed diagnosis of retinoblastoma, in the Hospital Infantil de Mexico Federico Gomez, in the period between January 2009 and January 2010. We compared the thickness of the optic nerve as measured by CT with the thickness obtained in the pathological piece.
Results: Of the 22 cases studied, CT diagnosed 8 patients with optic nerve invasion, of which there was good histopathological correlation in 4. In 13 patients were excluded optic nerve invasion tomography with histopathologic correlation in 11 cases, and in two cases histopathology confirmed the invasion of the optic nerve, but no imaging study would have suspected it.
Conclusion: CT has a high specificity to exclude optic nerve invasion to evaluate changes in intensity and thickness of the optic nerve, but is not as specific for the diagnosis of optic nerve invasion based only on the thickness of it, for which we advised not to use this as a basis for diagnosis.

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