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2011, Number 2

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Rev Mex Med Transfus 2011; 4 (2)

Transfusion science: Integration of proteomics with blood banking

Schubert P, Devine DV

Language: English
References: 57
Page: 38-47
PDF size: 87.21 Kb.


ABSTRACT

Blood banking comprises a constellation of activities from blood collection to testing and processing into individual blood components for transfusion purposes in which we seek to ensure the highest possible quality and safety. Challenged by the never-ending concerns and optimization endeavours of blood bank practice, research in transfusion medicine is currently tailored towards analyses of a variety aspect and issues spanning from donor to recipient. Over the last few years, proteomics technologies have been proven to be a valuable tool in transfusion research to tackle some of the unanswered questions in transfusion medicine. These studies include the storage lesions of platelet and red cell concentrates, changes in the platelet proteome during treatment with pathogen reduction technologies and quality assessment of plasma products. This review summarizes the current status of proteomic applications to blood banking and provides a perspective of the future.


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