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2011, Número 2

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Rev Mex Med Transfus 2011; 4 (2)


Ciencia de transfusión: Integración de la proteómica, con bancos de sangre

Schubert P, Devine DV

Idioma: Ingles.
Referencias bibliográficas: 57
Paginas: 38-47
Archivo PDF: 87.21 Kb.


RESUMEN

El trabajo en los bancos de sangre comprende una gama de actividades desde la donación sanguínea hasta la validación y obtención de componentes con fines terapéuticos, tratando de alcanzar la máxima calidad y seguridad. La investigación en medicina transfusional, desafiada siempre por las interminables preocupaciones y esfuerzos por optimizar las prácticas de los bancos de sangre, está enfocada actualmente hacia el análisis de una serie de aspectos y resultados que van del donador al receptor. En los años recientes, la tecnología proteómica ha demostrado ser una valiosa herramienta en la investigación transfusional para abordar algunas de las preguntas sin respuesta en medicina transfusional. Esto incluye estudios sobre las lesiones de almacenamiento de las plaquetas y concentrados de eritrocitos, cambios en el proteoma de las plaquetas durante el tratamiento con las tecnologías de reducción de agentes patógenos y la evaluación de calidad de los productos del plasma. Esta revisión resume el estado actual de las aplicaciones de la proteómica en los bancos de sangre y proporciona una perspectiva del futuro.


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