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Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

2009, Number 2

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Rev Esp Med Quir 2009; 14 (2)

Proposal for identifying genomic disorders to gestational diabetes in Mexican population

Silva XCA, Escobedo AF, Tusie LMT

Language: Spanish
References: 34
Page: 83-87
PDF size: 234.25 Kb.


ABSTRACT

Diabetes mellitus is among the primary mortality and morbidity causes in Mexico. Genetic factors play a fundamental role in the development of this entity. In the past few years due to the recognition and study of families with monogenic forms of diabetes and dyslipidemias associated with development of atherosclerosis, several genes and loci have been associated with this condition through genetic linkage studies. These studies have provided evidence of the genetic heterogeneity that exists and the type of genes involved in different ethnic groups. The study of Mexican families with early-onset diabetes gestational showed the participation of different genetic loci associated with these conditions in the Mexican population. These findings show the value of gene mapping strategies in the identification of the genetic component in these entities in our population.


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