2009, Número 2
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Rev Esp Med Quir 2009; 14 (2)
Propuesta para identificar alteraciones genómicas para diabetes gestacional en población mexicana
Silva XCA, Escobedo AF, Tusie LMT
Idioma: Español
Referencias bibliográficas: 34
Paginas: 83-87
Archivo PDF: 234.25 Kb.
RESUMEN
La diabetes mellitus figura entre las primeras causas de mortalidad y morbilidad en México. Factores genéticos juegan un papel fundamental en la evolución de esta enfermedad. A partir del reconocimiento y estudio de familias con formas monogénicas de diabetes, y distintas dislipidemias asociadas con aterosclerosis, se han identificado en los últimos años distintos genes y locus relacionados con este padecimiento a través de estudios de mapeo genético. Estos estudios han evidenciado la heterogeneidad genética de los tipos de genes implicados en los distintos grupos étnicos. El estudio de familias mexicanas con diabetes gestacional mostró la participación de distintos locus genéticos relacionados con esta enfermedad en la población mexicana. Esto muestra la utilidad de las estrategias de mapeo para la identificación del componente genético de esta enfermedad en nuestra población.
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