2010, Number 1
<< Back Next >>
Rev Esp Med Quir 2010; 15 (1)
Electroencephalogram findings in refractory epilepsy at National Medical Center 20 de Noviembre
Hernández CJ, Varela BJ, Álvarez NS, García S
Language: Spanish
References: 18
Page: 11-17
PDF size: 261.05 Kb.
ABSTRACT
Objective: To evaluate the superficial electroencephalographic characteristics in patients with refractory epilepsy from the Neurophysiologic Service of Centro Médico Nacional 20 de Noviembre.
Patients and method: In a prospective study, 43 patients with refractory epilepsy were included. It were made four interictal studies in each subject. 10-20 system electrodes placement and a conventional activation maneuvers were used. Visual analysis was made for diagnostic interpretation.
Results: 58.1% were female and 41.9% male. Groups from 20 to 29 years old and from 40 to 49 years old were the most frequent; both were 55.8% of sample. The first study showed abnormalities in 94% with focal alterations in 82.4% of them and generalized alterations in 11.6%, normal studies were obtained in 6%. In the second study abnormalities were found in 97.7% with focal alterations in 88.5% and generalized alterations in 9.2%, normal study in 2.3%. In the third register 95.3% were abnormal studies of which were focal alterations in 86%, generalized alterations in 9.3% and without alterations in 4.6%. In the fourth register 93% of abnormal register was found, 83.7% with focal alterations, 9.3% widespread alterations and 7% of them was normal.
Conclusions: Conventional register electroencephalogram is an excellent diagnostic method to detect electrical abnormalities in patients with refractory epilepsies. Interictal left temporal focal alterations were the most frequent.
REFERENCES
Bernard S, Chang MD, Daniel H, Lowestwin MD. Epilepsy, Mechanisms of disease. N Engl J Med 2003;349:1257-1266.
Fisher RS, van Emde Boas W, Blume W, et al. Epileptic seizures and epilepsy: Definitions proponed by International League Against Epilepsy (ILAE) and de International Bureau for Epilepsy (IBE). Epilepsia 2005;46:470-472.
Menchaca Salazar AJ, Hernández Cervantes J, Varela Blanco J. Utilidad del electroencefalograma del superficie en la evaluación prequirúrgica de los pacientes con epilepsia refractaria: Comparación de dos métodos Rev Esp Med Quir 2006;11:49-53.
RiegerJS. Actualizaciones en epilepsia. Neurol Supl 2006;2(1):19-25.
Salas PJ, Gil NA. La Clasificación las Crisis y Síndromes Epilépticos: Nuevas Propuestas. Neurología 2004;419(2):59-62.
Gil NA, Parra J. Manual de electroencefalografía. Mc Graw-Hill/Interamericana, 2002.
Devisnky O, Nelly K. Clinical and EEG features of simple partial seizures. Neurology 1998;38:1347-1352.
Blume WT. Interictal Electroencephalography in Neocortical Epilepsy. In Luders HO, Coimar YG, editors. Epilepsy surgery. Philadelphia: Lippincott Williams and Wilkinson, 2001.
Drury I, Beydoun A. Interictal epileptiform activity in elderly patients with epilepsy EEG. Clin Neurophysiol 1998;106:369-373.
Van Cott AC. Epilepsy and EEG in the elderly. Epilepsia 2002;43(Suppl. 3):94-102.
Campos GM, Kanner A. Epilepsias diagnóstico y tratamiento. Mediterráneo, 2004.
Kwan P, Brodie MJ. Early identification of refractory epilepsy. N Engl J Med 2000;342:314-319.
Carrizosa MJ, Cornejo-Ochoa W. ¿Qué es la epilepsia refractaria? IATREIA 2003;2:163-167.
Devinsky O. Patient with refractory seizure. N Engl J Med 1999;340:1565-1570.
Ruiz Sandoval JL, González Cornejo S. Identificación de áreas corticales anormales en epilepsia refractaria. Rev Mex Neuroc 2006;7(6):596-598.
Lowestein DH, Pharm KA. Status epilepticus. N Engl J Med 1998;338:970-976.
Plascencia M, Shorvon SD. Prevalence and incidence of epileptic seizures in an Andean region of Ecuador. Brain 1992;115:771-782.
Taylorm I, Scheffer HI. Occipital epilepsies: identification of specific and newly recognized syndromes Brain 2003;126:753-769.