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2002, Number 4

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Med Sur 2002; 9 (4)

Isolated limb perfusion. One option to the amputation in advanced tumors for melanoma, sarcomas and other unresectable tumors of the extremities

Martínez SH, Herrera GA, Aguilar PJL, Garza SJG

Language: Spanish
References: 66
Page: 148-155
PDF size: 149.66 Kb.


ABSTRACT

The Isolated Limb Perfusion is an old technique widely used in the treatment of in transit metastases for melanoma since 1959. The overall response rate are nearly 100% with the different chemotherapy schemes and schedules. With this experience and the developing of necrosis tumoral factor, the soft tissue sarcomas have been included in the indications for the perfusion. The response rate obtained in sarcomas, are excellent, with pathologic complete response about 37% and global response in near 95%. Actually the Isolated Limb Perfusion allows a limb sparing procedure in 90% of the cases.


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