2009, Number 590
Aspirina vs. Clopidogrel en la prevención secunadaris de cardiopatía isquémica
Holtermann H, Podetti C
Language: Spanish
References: 44
Page: 339-343
PDF size: 362.37 Kb.
ABSTRACT
An acute myocardial infarction involves necrosis of cardiac muscle secondary to prolonged isquemia. According to the WHO cardiovascular disease causes 16.7 million deaths per year worldwide. In our country it was the principal cause of death during 2004. Due to these facts, clopidogrel and aspirin used as secondary prevention were compared. Studies analyzed dealt with the risk-benefit and cost-benefit of these medications. It was found that both medicines were useful in cardiovascular disease prevention. The mayor difference was the reduction of complications and rehospitalization in patients treated with Clopidogrel. The cost of Clopidogrel is greater than Aspirin; therefore it was determined that proper classification of patients is necessary to determine the use of this medication. Aspirin being more cost-effective continues to be the gold standard for secondary prevention.REFERENCES
Mark DB, Cowper PA, Berkowitz SD, et al. Economic assessment of low-molecular-weight heparin (enoxaparin) versus unfractionated heparin in acute coronary syndrome patients: results from the ESSENCE randomized trial. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q wave Coronary Events [unstable angina or non-Q-wave myocardial infarction]. Circulation 1998;97:1702-7.