2010, Number 1
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Bol Clin Hosp Infant Edo Son 2010; 27 (1)
Infecciones por Virus Respiratorios en Menores de Dos Años Atendidos en el Hospital Infantil del Estado de Sonora
Cano-Rangel MA, Espinoza A, Durazo-Arvizu MÁ, Dórame-Castillo R, Cano-Corella MA
Language: Spanish
References: 21
Page: 4-8
PDF size: 122.85 Kb.
ABSTRACT
Objective: To know the local epidemiology of the lower respiratory tract infections by viruses in children under two.
Material and Methods: A prospective, transversal, observational and descriptive study was designed, which included years under two. They had lower tract infection between September 15, 2008 and July 15, 2009 demonstrated by direct immunofluorescence. Results will be presented in a statistical descriptive manner, conveniently displayed in charts and graphs.
Results: 164 samples were sent to the Sonora’s State Public Health Laboratory, from which two were rejected because of inappropriate identification, hence 161 samples were included. In 71 samples the viral agent was properly identified, 87% were respiratory syncytial virus (RSV); Influenza A 8.4%; adenovirus 2.5%; parainfluenza virus 1.3%.
From 62 infected patients with RSV, 42 (74.2%) were infants under 6 months, this increased up to 95% at the end of the year. Clinical presentation of RSV infection was pneumonia, followed by bronchiolitis and pertussis like syndrome.
Conclusions: knowledge of local epidemiological data, will allow us to use antibiotics judiciously, and to design studies that evaluate novel therapies in patients with severe evolution, allowing us to improve patient care.
REFERENCES
Sistema único para la vigilancia epidemiológica /dirección general de epidemiología/SSA, información on line http://www.dgepi.salud.gob.mx/anuario/html/anuarios.html
Bustamante CM, Velásquez RF, Cabrera ML.et al. Molecular detection of respiratory syncytial virus in postmortem lung tissue samples from Mexican Children deceased with pneumonia. Pediatr infect Dis J 2001; 20: 4 95-501.
Cano MA, Álvarez HG, Dorame CR, Contreras SJ. Infecciones por virus respiratorio sincicial en pediatría. Bol Clin Hosp Infant Edo Son 2007; 24: 73-80.
Byngton CL, Castillo H, Gerber K, Daly JA, Breinley LA. Et al. The Effect of Rapid Respiratory Viral DiagnosticTesting on Antibiotic Use in a Children’s Hospital. Arch Pediatr Adolesc Med. 2002; 156: 1230-4.
Fernandez RM. Los aerosoles con suero salino hipertónico al 3% podrían disminuir la duración de la hospitalización en lactantes con bronquiolitis.Evid Pediatr 2007; 3: 102.
Tal G, Cesar K, Oron A, est al. Hypertonic saline/epinefrine treatment in hospitalized infants with viral bronchiolitis reduces hospitalization stay: 2 years experience. IMAJ 2006 ;8: 189-73.
Kimpen J, Manegement of respiratory syncytial virus infection. Curr Opin Infect Dis 2001; 14: 323-8.
Ruiz CM, Castillo RR, Bermúdez FF. Factores de riesgo asociados a bronquiolitis en niños menores de dos años. Rev Inves Clin 2002; 54: 125-132.
Woensel J, Aalderen W, Kimpen J. Viral lower respiratory tract infection in infants and young children. BMJ 2003; 327: 36-40.
Wolf DG, Greenberg D, Kalkstein D, et al. Comparision of human metapneumovirus, respiratory syncytial virus and influenza A virus lower respiratory tract infection in hospitalized young children. Pediar Infect Dis J 2006; 25: 320-4.
Escorihuela E, Fernández JA, Millan JA. Uso de antibióticos en niños hospitalizados por infección respiratoria aguda. An Pediatr (Barc) 2000; 52: 148-56.
Kaygusuz S, Koksal I, Aydin K and Caylan R. Investigation of atypical bacteria and virus antigens in respiratory tract infections by use of immunofluoresence method. Jpn J Infect Dis 2004; 57: 33-6.
Simoes EA, Carbonell EX, Impact of severe disease caused by respiratory syncytial virus in children living in developed countries. Pediatr Infec Dis J 2003; 22: s13-20.
Kareaga NA, Montes M, Perez-Yarsa EG, Sardon o, et al. Características clínicas de los niños hospitalizados por infección de virus de la influenza. An Pediatr (Barc)2005; 62: 5-12.
Mejías A, Chávez BS, Ramilo O. Respiratory syncytial virus pneumonia: mechanisms of inflammation and prolonged airway hyperresponsiveness. Curr Opin Infect Dis 2005; 18; 199-204.
Escribano MA, De Juanes PJ. Infección por el virus de la influenza en la infancia. ¿Deberan ampliarse las indicaciones de la vacuna antigripal?. Arch Bronconeumol 2004; 40: 231-5.
Hasan SJ, Treatment of respiratory Syncytial virus: Antiviral terrapies. Pediatr Infect Dis J 2003; 22: s89-93.
Welliver RC. Respiratory syncytial virus and other respiratory viruses. Pediatr Infect Dis J. 2003; 22: S6-12.
Gern JE. Viral and bacterial infections in the development and progression of asma. J Allergy Clin Immunol 2000; 105: S497-502.
Ventre K, Haroon M, Davison C. Surfactant therapy for bronquiolitis in critically ill Infant (review). The Cochrane collaboration published by John Wiley & son,LTD 2006.
Cambonie G, Milesi C, Founier S et al. Clinical effects of heliox administration for acute bronquiolitis in young infants. Chest 2006; 129: 676-82.