medigraphic.com
Órgano Oficial del Instituto de Ciencias de la Salud, Hospital Escuela y Facultad de Medicina-Xalapa

2003, Number 2

<< Back

Rev Med UV 2003; 3 (2)

Papel del músculo pubococcigeo en el proceso de continencia urinaria en la rata macho

Manzo J, Esquivel A, Hernández MA, Carrillo P, Gómez M, Pacheco P

Language: Spanish
References: 19
Page: 34-42
PDF size: 640.89 Kb.


ABSTRACT

The role of the male rat pubococcygeus muscle (Pcm) in the micturition reflex was analyzed. Anatomical features of Pcm, electrical stimulation of its nerve, electrical recording and stimulation of the muscle and cystometrograms were carried out. Results showed that Pcm has fibers attached to the ventrolateral part of the external uretrhral sphincter, and that its activity contributes to hold the tail in the midline. Pcm shows activity during fluid expulsion in cystometrograms and spontaneus micturitions. This activity produced reflex inbhition of detrusor contraction and was not the cause of intravesical high frecuency oscillations. Thus, it is proposed that Pcm activity produces the discharge of its afferents wich in turn activates a spinal reflex to promote continence.


REFERENCES

  1. Brink, E.E and Pfaff, W. D. . Vertebral muscles of the back and tail of the albino rat (Ratus norvergicus albinos). Brain Behav. Evol., 17: 1,1980.

  2. Pacheco, P., Martínez-Gómez, M., Whiple, B, Beyer, C. AND Komisaruk, B.R. : Somatomor components of the pelvic and pudendal nerves of the female rat. Brain Res., 490: 85, 1989.

  3. Lucio, R.A., Manzo, J., Martínez- Gómez, M., Sach, B.D. and Pacheco, P.: Participation of pelvic nerve branches in male rat copulatory behavior. Physiol. Behav., 55: 241, 1994.

  4. Gilpin, S.A., gosling, J.A., Smith, A.R.B. and Warrel, D.W.: The pathogenesis of genitourinary prolapse and stress incontinence of urine. A histological and histochemical study. Br. J. Obstet. Gynaecol., 96: 15, 1989.

  5. Whishaw, M.K. and Fonda, D. :Is there a role for drug therapy in the treatment of urinary incontinence in the elderly? Med. J. Australia, 160: 430, 1994.

  6. Dubrovsky, B. and Filipini, D.: Neurobiological aspects of the pelvic floor muscles in defecation. Neurosci. Biobehav. Rev. 14:157, 1990.

  7. Mano, J. Esquivel A., Vazquez, M.I., Cruz, Y. And Pacheco, P.: Striated muscle activity during the mictutition reflex in the rat and mictutition patterns in a sexual context. Soc. Neurosci. Abstr., 20:1754, 1994.

  8. Maggi, C.A., Giuliani, S., Santicioli, P. And Meli, A.: Analysis of factors involved in determining urinary bladder voiding cycle in urethane anesthetized rats. Am. J. Physiol., 251: R250, 1986.

  9. Malorry, B.S., Steers, W.D and deGroat, W.C..: Electrophysiolocical study of micturition reflexes in rats. Am J. Physiol., 257:R414, 1989.

  10. deGroat, W.C., and Steers, W.D.: Autonomic Regulation of the urinary bladder and sexual organs. In: Central egulation of Autonomic Functions. Edited by A.D. Loewy and K.M Spyer. New York. Oxford University Press, pág. 310-333, 1990.

  11. Kruse, M.N., Noto, H., Roppolo, J.R. and de Goat, W.C: Pontine control of the urinary bladder and external urethral sphincter in the rat. Brain Res. 532: 182, 1990.

  12. Setchell, B.P., Maddocks, S. and Brooks, D.E.: Anatomy, vasculature, innervation, and fluids of the male reproductive tract. In: The Physiology of Reproduction. Edited by E. Knobil and J. Neill. New York: Raven Press, Ltd. 2nd edition, pág. 1063-1776, 1994.

  13. Kuru, M.: Nervous control of miscutrition. Physiol. Rev., 45: 425,1965.

  14. Nishizawa, O., Satoh, S., Harada, T., Nakamura, H. Fukuda, T., Tsukada,T. And Tsuchida, S.: Role of the pudendal nerves on the dynamics of micturition in the dog evaluated by pressure flow EMG and pressure flow plot studies. J. Urol., 132: 1036, 1984.

  15. Sachs, B.D and Liu, Y-C.: Copulatory behavior and reflexive peline erection in rats after section of the pudendal anf genitofemoral nerves. Physiol. Behav., 51 673, 1992.

  16. Honda,C.N.: visceral and somatic affernt convergence onto neurons near the central canal in the sacral spinal cord of the cat. J. Neurophysiol., 53: 1059, 1985.

  17. Dubrovsky, B., Martínez- Gómez, M., Pacheco, P.: Spinal control of pelvic floor muscles. Exp. Neurol., 88: 277, 1985.

  18. Elbadawi, A.and Schenk, E.A.: A new theory of the innervation of bladder musculature. IV. Innervation of the vesicourethral junction and external urethral sphincter. J. Urol., 111: 163, 1974.

  19. Brindley, G.S.: Treatment of urinary and faecal incontinence by surgically implanted devices. In Neurobiology of Incontinence(Ciba Fundation Symposium 151). Chichester: Wiley, pp. 267-282, 1990




2020     |     www.medigraphic.com