2009, Number 3
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Rev Mex Urol 2009; 69 (3)
The cranberry and its application in urology
De-León-Jaén SC, Ovadía-Rosenfeld L, Vásquez-Delgado LR, Fainsod-Aronowitz T
Language: Spanish
References: 33
Page: 104-107
PDF size: 1944.18 Kb.
ABSTRACT
The cranberry has been used throughout history as treatment for urinary infections. It was thought to acidify urine but recent studies have shown that the activity of its principal substances, fructose and anthocyanidins, hinder E. coli bacterium adhesion to the urothelium. This has been shown to be predominant in women but not in neurogenic bladder patients. The present review concludes that the cranberry acts as a preventive agent against urinary infections rather than as a treatment for them. Multiple studies are being carried out to determine the usefulness of anthocyanidins in other organs.
REFERENCES
Jepson RG, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2008, Issue 1. Art No. CD001321. DOI: 10.1002/14651858.CD001321.pub4 [consultado 2009 junio 11]. Disponible en: http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD001321/frame.html
Jepson RG, Mihaljevic l, Craig J. Cranberries for preventing urinary tract infections. Cochrane Library 2004; 1:1-19.
Raz R, Chazan B, Dan M. Cranberry juice and urinary tract infection. Clin Infect Dis 2004 May 15;38(10):1413-9.
Zafriri D, Ofek I, Adar R et al. Inhibitory activity of cranberry juice on adherence of type 1 and type P fimbriated Escherichia coli to eukaryotic cells. Antimicrob Agents Chemother 1989;33:92-8.
Howell AB, Vorsa N, Der Marderosian et al. Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthocyanidin extracts from cranberries. N Engl J Med 1998 Oct 8;339:1085-6.
Foo L, Lu Y, Howell AB et al. A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli. J Nat Prod 2000;63:1225-8.
Howell AB, Reed JD, Krueger CG et al. A-type cranberry proanthocyanidins and uropathogenic bacterial anti-adhesion activity. Phytochemistry 2005 Sep;66:2281-91.
Vinson JA, Su X, Zubik L et al. Phenol antioxidant quantity and quality in foods: fruits. J Agric Food Chem 2001 Nov;49:5315-21.
Sobota AE. Inhibition of bacterial adherence by cranberry juice: potential use for the treatment of urinary tract infections. J Urol 1984 May;131:1013-6.
Avorn J, Monane M, Gurwitz JH, et al. Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA 1994 Mar 9; 271:751-4.
Stothers L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can J Urol 2002 Jun;9:1558-62.
Howell AB, Foxman B. Cranberry juice and adhesion of antibioticresistant uropathogens. JAMA 2002 Jun 19;287:3082-3.
Chambers BK, Camire ME. Can cranberry supplementation benefit adults with type 2 diabetes? Diabetes Care 2003;26(9):2695-6.
Crews WD Jr, Harrison DW, Griffin ML et al. A double-blinded, placebo- controlled, randomized trial of the neuropsychologic efficacy of cranberry juice in a sample of cognitively intact older adults: pilot study findings. J Altern Complement Med 2005 Apr;11:305-9.
Elliott SP, Villar R, Duncan B. Bacteriuria management and urological evaluation of patients with spina bifida and neurogenic bladder: a multicenter survey. J Urol 2005;173(1):217-20.
Gettman MT, Ogan K, Brinkley LJ et al. Effect of cranberry juice consumption on urinary stone risk factors. J Urol 2005 Aug;174:590-4; quiz 801.
Grant P. Warfarin and cranberry juice: an interaction? J Heart Valve Dis 2004 Jan;13:25-6.
Howell AB, Foxman B. Cranberry juice and adhesion of antibioticresistant uropathogens. JAMA 2002;287:3082-3083.
Weiss El, Lev-Dor R Kashman Y, Goldhar J et al. Inhibiting interspecies coaggregation of plaque bacteria with a cranberry juice constituent. J Am Dent Assoc 1998;129:1719-23.
Chen L, Heber D, Hardy M et al. Inhibitory effects of Cranberry on Streptococcus mutans biofilm formation. Presented at IADR/AADR/CADR 82nd General Session; 2004 March 13; Honolulu (HI), USA.
Kontiokari T, Sundqvist K, Nuutinen M et al. Randomised trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. BMJ 2001;322:1-5.
Linsenmeyer TA, Harrison B, Oakley A et al. Evaluation of cranberry supplement for reduction of urinary tract infections in individuals with neurogenic bladders secondary to spinal cord injury. A prospective, double-blinded, placebo-controlled, crossover study. J Spinal Cord Med 2004;27:29-34.
Shmuely H, Yahav J, Samra Z et al. Effect of cranberry juice on eradication of Helicobacter pylori in patients treated with antibiotics and a proton pump inhibitor. Mol Nutr Food Res 2007 Jun;51:746-51.
Waites KB, Canupp KC, Armstrong S et al. Effect of cranberry extract on bacteriuria and pyuria in persons with neurogenic bladder secondary to spinal cord injury. J Spinal Cord Med 2004;27:35-40.
Zhang L, Ma J, Pan K, et al. Efficacy of cranberry juice on Helicobacter pylori infection: a double-blind, randomized placebo-controlled trial. Helicobacter 2005 Apr;10:139-45.
Yamanaka A, Kimizuka R. Kato T, Okuda K. Inhibitory effects of cranberry juice on attachment of oral streptococci and biofilm formation. J Oral Microbiol Immunol 2004;19:150-4.
Burger O, Ofek I, Tabak M et al. A high molecular mass constituent of cranberry juice inhibits Helicobacter pylori adhesion to human gastric mucus. FEMS Immunol Med Microbiol 2000 Dec;29:295-301.
Cohen P, Lipson S. Mechanism(s) of inactivation by the American cranberry (Vaccinium Macrocarpon) of mammalian enteric viruses. American Society for Microbiology´s 105th General Meeting; 2005 Jun 5-9; Atlanta (GA), USA.
Wilson T, Porcari JP, Harbin D. Cranberry Extract Inhibits Low Density Lipoprotein Oxidation. Life Sci 1998;62(24):PL381-6.
Weiss EI, Houri-Haddad Y, Greenbaum E et al. Cranberry juice constituents affect influenza virus adhesion and infectivity. Antiviral Res 2005 Apr;66:9-12.
Neto CC, Krueger CG, Lamoureaux TL et al. MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitro. J Sci Food Agric 2006:86;18-25.
Campbell G, Pickles T, D´yachkova Y. A randomized trial of cranberry versus apple juice in the management of urinary symptoms during external beam radiation therapy for prostate cancer. Clin Oncol (R Coll Radiol) 2003 Sep;15:322-8.
Bailey DT, Dalton C, Daugherty FJ et al. Can a concentrated cranberry extract prevent recurrent urinary tract infections in women? A pilot study. Phytomedicine 2007 Apr;14:237-41.