López-Chiñas A, Lugo-García JA, Viveros-Contreras C, Olguín-Nava H, Montero-López P, Hernández-Merino MA

Language: Spanish
References: 13
Page: 13-16
PDF size: 366.02 Kb.

ABSTRACT

Mobile sperm count has been observed to have a tendency to diminish to the degree that cancer stage increases in patients depositing their semen in a sperm bank. In one study mean spermatozoid concentration in patients presenting with seminomas was 50 million/ml, while in patients presenting with non-seminomatous germ cell tumors (NSGCT) the mean decreased to 17 million/ml.
Objective. To evaluate the relation between histopathological presentation and seminogram results in patients having undergone radical orchiectomy in the Urology Service of the Hospital Juárez de México.
Materials and Methods. From March 2006 to May 2007 an original clinical longitudinal prospective study was carried out in testicular tumor patients from the Urology Service of the Hospital Juárez de México, who underwent radical orchiectomy. Direct preoperative spermatobioscopy was carried out on all patients and the results were statistically analyzed in relation to tumor type, stage and progression.
Results. A total of 22 radical orchiectomies were performed. Eighteen patients presented with spermatobioscopy alterations. Six of those patients presented with 1 alteration and 12 patients with 2 or more. Necrospermia, hypospermia and astenospermia were the predominating alterations.
Conclusions. There is a relation between testicular cancer and seminogram alterations. Histological type, progression and tumor stage are directly related to specific alterations in the seminogram results.

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