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Revista Mexicana de Urología

Organo Oficial de la Sociedad Mexicana de Urología
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2010, Number 4

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Rev Mex Urol 2010; 70 (4)

Leydig cell tumor in 86-year-old man

García-Rodríguez MA, Zenil-Medina A, Colorado-García Alberto, Vilchis-Cárdenas MA, Torres-Medina E
Full text How to cite this article

Language: Spanish
References: 6
Page: 254-256
PDF size: 3645.18 Kb.


Key words:

Leydig cells, testicular tumor, virilization, feminization, Mexico.

ABSTRACT

Leydig cell testicular tumors are derived from non-germ cells and have a very low incidence rate that is estimated at 2 cases per 100,000 inhabitants, representing 1% of testicular tumors. These tumors appear between the ages of 20-60 years in 80% of cases.
The case presented here is an 86-year-old man with increase in volume of the right testis and orchialgia of approximately 1-year progression. Tumor was detected in right testis by means of ultrasound. Physical examination did not reveal clinical signs of endocrine involvement. Lactate dehydrogenase, alpha-fetoprotein and chorionic gonadotropin beta subunit were in normal ranges. Abdominal computed tomography and chest x-ray showed no abnormalities. After right radical orchiectomy was carried out, non-malignant Leydig cell tumor was reported. The appearance of tumor in a patient of such advanced age was striking given that there are very few such cases reported in the literature.


REFERENCES

  1. Laguna MP, Pizzocaro G, Klepp O. EAU Guidelines on testicular cancer. Eur Urol 2001;40(2):102-10.

  2. Rubio Tortosa I, Rodrigo Guanter V, García Torrelles M. Leydig cell tumor: our experience. Bibliographic review. Arch Esp Urol 2006;59(5):467-72.

  3. Kim I, Young RH, Scully RE. Leydig cell tumor of the testis. A clinical pathological analysis of 40 cases and review of the literature. Am J Surg Pathol 1985;9(3):177-92.

  4. Valero G. Tumor testicular de células de Leydig. Rev Chil Urol 2004;69(2):183-4.

  5. Loeser A, Vergho DC, Katzenberger T. Testis-sparing surgery versus radical orchiectomy in patients with Leydig cell tumors. Urology. 2009;74(2):370-2.

  6. Acar C, Gurocak S, Sozen S. Current treatment of testicular sex cordstromal tumors: critical review. Urology 2009;73(6):1165-71.




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Rev Mex Urol. 2010;70