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ISSN 0188-9796 (Print)

2010, Number 3

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Rev Endocrinol Nutr 2010; 18 (3)

Impact of oxygen reactive species on male fertility

Hernández-Matos Y, Delgado-Roche L, López-Pérez R, Martínez-Sánchez G, Mallok A

Language: Spanish
References: 30
Page: 153-158
PDF size: 278.38 Kb.


ABSTRACT

During the past decade, reactive oxygen species have emerged as important regulators of many physiological and pathophysiological processes, including the role they play in male fertility. At low and normal concentrations, they are essential in the spermatozoid capacitation process. While high levels caused by an increase in its generation or dysfunctional antioxidant systems, reactive oxygen species cause DNA damages and induce peroxidative process on cellular membranes. Under these conditions the sperm viability is affected and consequently the male fertility. The aim of the present work was to investigate the role of reactive oxygen species and oxidative stress on male to fertility.


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