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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2010, Number 4

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An Med Asoc Med Hosp ABC 2010; 55 (4)

Fundus flavimaculatus

Turrión SE

Language: Spanish
References: 17
Page: 212-216
PDF size: 310.31 Kb.


ABSTRACT

Stargardt´s disease and fundus flavimaculatus are different stages of a single disease. It is an autosomal recessive disorder due to a mutation of the ABCR gen. Patients present nictalopia and metamorphopsia. Characteristic lesions are yellowish-white lesions or flecks. Histopathologic evaluation of the eye, revealed lipofuscin in the retinal pigment epithelium. In approximately 90% of patients, the fluorescein angiogram exhibits a phenomenon known as dark choroid. The full field electroretinogram in an early course of the disease is normal but the foveal or focal electroretinogram is reduced in amplitude or delayed in implicit time. There is no treatment for this disease and genetic counseling is recommended. We describe a patient with the diagnosis of fundus flavimaculatus.


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