2010, Number 1
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Patol Rev Latinoam 2010; 48 (1)
Neuroenterogenous cyst of cerebellopontine angle
Rembao BD, Martínez ZC, Maldonado MM, Becerra ÄF, Gómez GD, Romero S, García MA, Tena SML, Salinas LC
Language: Spanish
References: 22
Page: 26-31
PDF size: 272.19 Kb.
ABSTRACT
Enterogenous cysts are rare, benign lesions involving the spinal canal and the cerebellopontine angle. Usually they present compression of the spinal cord or cranial nerves. These lesions are 1 cm or less in size and are usually lined by columnar mucin-producing epithelium resembling enteric epithelium or columnar ciliated epithelium resembling respiratory epithelium. We report the case of a 58-year-old male with occipital cephalea, visual disturbance and vertigo. MRI and CAT imaging showed a cerebellopontine angle enhancement suggested cyst neurocisticercosis. He was treated with albendazol (30 mg/kg) and steroids by two years without clinical improvement. Near total excision of the cyst was carried out through the retro mastoid route. Patient made a good postoperative recovery. Histologically corresponded to an enteric cyst, was stained with AA, PAS and mucicarmine positive; and immunohistochemical stains including: epithelial membrane antigen, cytokerain 8 and cytokeratin 5/6 were positive. The histopathologic, ultrastructural, and inmunologic findings in these lesions are similar to those present in the bronchial epithelium, supporting the hypothesis of endodermal origin for these lesions. Cord malformations derive from defects in these early embryonic stages, and are collectively called spinal dysraphisms.
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