Díaz PH, Montes DR, Solórzano SF, Benítez AH, López AE, Ruiz RA, Guillén CTJ

Language: Spanish
References: 11
Page: 15-18
PDF size: 72.05 Kb.

ABSTRACT

In order to know the prevalence of Aspergillus colonization of the upper tract airways in cancer patients a prospective study was performed. One hundred patients hospitalized at the Hospital Anexo de Pediatría (N = 68) and at the Hospital de Pediatría (N = 32) from the Centro Médico “Siglo XXI” were included. One sample from the nose of each patient was taken and cultured on Sabouraud slants. Prevalence of Aspergillus colonization was 7%; Aspergillus niger was the species most commonly isolated.
Increased risk of colonization was noted for leukemic patients hospitalized at the Hospital Anexo, and those under chemotherapy and antibiotic treatment, but without statistical significative difference; time of evolution of underlying diseases resulted as a risk statistically significative (Kruskal-Wallis, p = 0.043).

REFERENCES

1. 1.Bennet J. “Aspergillus species”. En Mandel G, Douglas G, Bennett J. Principles and practice of infectious dis-eases. 3a. ed. Nueva York, Churchill Livingstone, 1990, 1558-1561.

2. 2.Bodey G, Vartivarian S. “Aspergillosis”. Eur J Microbiol Infect Dis 1989; 8: 413-437.

3. 3.Swatek F, Halde C, Rinaldi M, Shadomy J. «Aspergillus species and other opportunistic saprophytic hyaline hyphomycetes”. En Lennette E, Balows A, Husler W, Shadomy J, Manual of clinical microbiology, 4a. ed., Washington, D.C., American Society for Microbiology, 1985, 584-587.

4. 4.Arnow PM, Andersen RL, Mainous PD, Smith EJ. “Pul-monary aspergillosis during hospital renovation”. Am Rev Resp Dis 1978; 118: 49-53.

5. 5.Arnow PM, Sadigh M, Costas C,Weil D, Chudy R. “Endemic epidemic aspergillosis associated with in-hospital replication of Aspergillus organisms”. J Infect Dis 1991; 164: 998-1002.

6. 6.Sherertz R, Belani A, Barnett M et al. “Impact of air filtration on nosocomial Aspergillus infections”. Am J Med 1987; 83: 709-717.

7. 7.Aisner J, Murillo J, Schimpff S et al. “Invasive aspergil-losis in acute leukemia: Correlation with nose cultures and antibiotics use”. Ann Intern Med 1979; 90: 4-9.

8. 8.Treger T, Visscher M, Bartlett M. “Diagnosis infection caused by Aspergillus: Usefulness of respiratory cul-tures”. J Infect Dis 1985; 152: 572-576.

9. 9.Raccah R, Martino P, Gentile G et al. «Aspergillus colonization of the nose and pulmonary aspergillosis in neutropenic patients: A retrospective study”. Haema-tologica 1989; 74: 263-265.

10. 10.Jenicek M, Cleroux R. Epidemiología: Principios, téc-nicas y aplicaciones, 1a. ed., Barcelona, Salvat, 1987, 77-122.

11. 11.Dean AG, Dean JA, Burton AH, Dicken RC. “Analysis commands”. En Epi Info, version 6: A word processing, database, and statistics program for epidemiology on microcomputers. USD, Stone Moutain, Georgia, 1994, 313-362.