Hernández-Herrera RJ, Ramírez-Sánchez LF

Language: Spanish
References: 11
Page: 352-356
PDF size: 422.17 Kb.

ABSTRACT

Background: The incidence of multiple pregnancies has increased on the last decade resulting in a rise of premature and underweight newborns infants, with increase of the perinatal morbidity and mortality.
Objective: To determine the impact of perinatal mortality of multiple pregnancies in the total perinatal mortality.
Patients and method: perinatal mortality rate of multiple pregnancies treated in the Unidad Médica de Alta Especialidad No. 23, Monterrey, Nuevo León (Mexico) were analized, from 2002 to 2008. The prevalence of multiple pregnancies, the rate of premature births, the incidence of low-birth weight products and perinatal mortality was estimated. The difference between overall mortality and multiple pregnancy rate was measured by χ².
Results: Of the 144.114 births, there were 1,076 (0.8%) fetal deaths and 1,617 (1.10%) neonatal deaths. There were 110 high-order fetal pregnancies (more than three fetuses): 92 triplets, 14 quadruplets, 3 quintuplets and 1 sextuplet, producing a total of 353 newborns. Multiple pregnancies represent 2.8% (59/2,093) of the total perinatal mortality (p = 0.3). 79.9% (1,674/2,093) of the total perinatal mortality were newborns weighing less than 2,500 g. In the group of multiple pregnancies, all perinatal deaths occurred in products weighing less than 2,500 g.
Conclusions: The perinatal mortality of multiple pregnancies does not impact significantly overall perinatal mortality.

REFERENCES

1. Multiple gestation: complicated twin, triplet, and high-order multifetal pregnancy. ACOG Practice Bulletin No. 56. American College of Obstetricians and Gynecologists. Obstet Gynecol 2004;104:869-883.

2. Martin JA, Park MM. Trends in twin and triplet births: 1980-97. Nat Vital Stat Rep 1999;47:24.

3. Blondel B, Kogan M, Alexander G, Datan N, et al. The impact of the increasing of the number of multiple births on the rates of preterm birth and low birthweigth: An International Study. Am J Public Health 2002;92(8):1323-1330.

4. Hernández HR, Ochoa TM, Flores SR, Cortes FR, Forsbasch SG. Prevalencia de embarazos múltiples: incremento en la última década. Ginecol Obstet Mex 2008;76(9):507-511.

5. Blondel M, Kaminski M. Trends in the occurrence, determinants, and consequences of multiple births. Semin Perinatol 2002;26(4):239-249.

6. Zuppa A, Scorrano A, Cota F, D’Andrea V, et al. Neonatal outcomes in triplet pregnancies: assisted reproduction versus spontaneous conception. J Perinat Med 2007;35(4)339-343.

7. Joseph KS, Marcoux S, Ohlsson A. Preterm birth, stillbirth and infant mortality among triplet births in Canada, 1985-96. Paediatr Perinat Epidemiol 2002;16(2):141-148.

8. Getahun D, Amre DK, Ananth CV, Demissie K, Rhoads GG. Temporal changes in rates of stillbirth, neonatal and infant mortality among triplet gestations in United States. Am J Obstet Gynecol 2006;195(6):1506-1511.

9. Kaufman GE, Malone FD, Harvey-Wilkes KB, Chelmow D, et al. Neonatal morbidity and mortality associated with triplet pregnancy. Obstet Gynecol 1998;91(3):343-348.

10. Hernández HRJ, Rayo ROY, Alcalá GLG, Ramos GR. Mortalidad perinatal en embarazos múltiples. Ginecol Obstet Mex 2009;77(3):247-250.

11. Gutiérrez SMA, Hernández HRJ, Luna GSA, Flores SR. Mortalidad perinatal en el Hospital de Ginecoobstetricia núm. 23 de Monterrey, Nuevo León (2002 a 2006). Ginecol Obstet Mex 2008;76(5):243-248.