2008, Number 11
<< Back Next >>
Ginecol Obstet Mex 2008; 76 (11)
Frequency of risk factors in breast cancer
Romero FMS, Santillán AL, Olvera HPC, Morales SMÁ, Ramírez MVL
Language: Spanish
References: 23
Page: 667-672
PDF size: 230.30 Kb.
ABSTRACT
Background: One in eight women has risk to developing breast cancer in long life (12.2%) one out of each 28 is in risk of death by this disease. The most recognized risk factors are hormonals, genetics and environmentals.
Objective: To identify the frequency of risk factors for breast cancer patients.
Patients and methods: A cross-sectional study was conducted in the Ambulatory Care Medical Unit 231, IMSS, in the medical records of 272 breast cancer patients in order to identify the major risk factors.
Results: 272 patients were studied, out of which 63 (23.1%) had no risk factor; 174 (64%) had 1 to 2 factors, 35 (12.9%) had 3 to 4 factors. The most common age group was 50-59 years. 80 women were menopausal, 28 (35%) had › 54 years, obesity was present in 35% of postmenopausal patients; with 29.8% of smokers, 16.9% had pregnancies long term › 30 years old. 14.3% were diabetics prior to breast cancer, and 12.2% had used exogenous hormones for › 5 years, 10.7% had experienced menarche ‹ 11 years. Family background in first degree was 6.6% and for another cancer 32.4%. The detection by self examination was 91.5% and 1.1% by mastography.
Conclusions: The most frequent risk factors included: overweight, obesity, smoking, exogenous hormones and pregnancy long term › 30 years. The method most frequently used for detection was self examination.
REFERENCES
Ferlay J, Bray F, Pisani P, Parkin DM. Globocan 2002: Cancer incidence, mortality and prevalence worldwide. ARC Cancer Base No 5, version 2·0. Lyon: ARC Press, 2004.
Sandoval GF, Cárdenas SJ. Segunda revisión del Consenso Nacional Sobre el Diagnóstico y Tratamiento del Cáncer Mamario. Colima, México. 2005. dirección URL:
American Cancer Society Surveillance Program. Estimated new cancer cases by sex and age Atlanta, American Cancer Society, 2003.
Secretaría de Salud. Registro histopatológico de neoplasias malignas. México: Dirección General de Epidemiología, SSA; 2001.
Amaro-Heredia M, Bautista-Samperio L, Arrieta-Pérez R. Correlación de factores de riesgo y hallazgos clínicos para cáncer mamario en pre y posmenopáusicas. Rev Fac Med UNAM 2007;50(3):110-4.
INEGI (2005). 4 de febrero, Día Mundial contra el Cáncer. Febrero. Dirección URL:
Rodríguez S, Carpuso M. Epidemiología del cáncer de mama. Ginecol Obstet Max 2006;74(11):585-93.
Rodriguez-Cuevas S, Macias CG, Franceschi D, Labastida S. Breast carcinoma presents a decade earlier in Mexican women than in the United States or European countries. Cancer 2001;91:863-8.
Torres-Arreola L, Vladislavovna-Dubova S. Cáncer de mama, detección oportuna en el primer nivel de atención. Rev Med Inst Mex Seguro Soc 2007;45(2):157-66.
Salazar-Esquivel E, Paredes-López A, Calzada-Sánchez L. Factores de riesgo hormonal durante la promoción, progresión y pronóstico tumoral mamario. Ginecol Obstet Méx 2004;72:545-9.
Cnattingius S, Torrång A, Ekbom A, Granath F, et al. Pregnancy characteristics and maternal risk of breast cancer. JAMA 2005;294:2474-80.
Singletary SE. Rating the risk factors for breast cancer. Ann Surg 2003;237:474-82.
Martínez-Abundis G, Cano-Ríos P, González-Hernández S, Rosales-Hernández F. Factores predisponentes al cáncer de mama en la Región Lagunera. Ginecol Obstet Mex 2004;72:525-30.
Song Y, Sung J, Ha M. Obesity and risk of cancer in postmenopausal Korean Women. J Clin Oncol 2008;26(20):3395-402.
Jee S, Yun J, Park E, Cho E, et al. Body mass index and cancer risk in korean men and women. Int J Cancer 2008;123(8):1892-6.
Heredia AM, Bautista LS. Correlación de factores de riesgo y hallazgos clínicos para cáncer mamario en pre y posmenopáusicas. Rev Fac Med UNAM 2007;50(3):110-4.
Blot WJ. Invited commentary: more evidence of increased risks of cancer among drinkers. Am J Epidemiol 1999:150:1138-40.
Castaño ME. Estilo de vida para prevenir el cáncer de mama, 2006. Dirección URL:
Lin Y, Kikuchi S, Tamakoshi K, Wakai K, et al. Active smoking, passive smoking and breast cancer risk: findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk. J Epidemiol 2008;18(2):77-83.
Wingo PA, Layde PM, Lee NC. The risk of breast cancer in postmenopausal women who have used estrogen replacement therapy. JAMA 1987;257:209-15.
Pirie k, Beral V, Peto R, Roddam A, et al. Passive smoking and breast cancer in never smokers: prospective study and meta-analysis. Int J Epidemiol 2008;3:110-3.
Trentham-Dietz A, Nichols H, Egan K, Titus-Ernstoff L, et al. Cigarette smoking and risk of breast carcinoma in situ. Epidemiology 2007;18(5):629-38.
Lissowska J, Brinton L, Zatosnki W, Blair A, et al. Tobacco smoking, NAT2 acetylation genotype and breast cancer risk. Int J Cancer 2006;119(8):961-9.