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Federación Mexicana de Ginecología y Obstetricia, A.C.

2008, Number 11

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Ginecol Obstet Mex 2008; 76 (11)

Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole

Hernández BJA, Vázquez AA, Olguín RC, Dumet HPF, Gutiérrez RM, De Zordo D

Language: Spanish
References: 24
Page: 652-658
PDF size: 366.80 Kb.


ABSTRACT

Background: Vaginitis is an inflammatory process in vaginal mucosa that affects millions of woman worldwide.
Objective: To evaluate prevalence perception and prescription preference among Latin-American gyneco-obstetricians in mixed vaginitis, and to identify attributes of various active principles.
Material and methods: multicentric and transversal study during January 2008. Close Up® was used to poll gyneco-obstetricians prescribing clyndamicin plus ketoconazole. 1,198 gyneco-obstetricians were selected to answer a poll (scales and measuring attributes) to identify differences among various therapeutic schemes to mixed vaginitis.
Results: 34% of gyneco-obstetricians consider that 30 to 50% of them patients had mixed vaginitis, 38% consider a 50 to 70% of its prevalence, and 20% a 70% or higher figure. In a bad to excellent scale, 97% had very good to excellent results with antimycotic and antibacterial mix, 73% had a bad to good result with antimycotics alone and 79% with antibacterial alone. Clyndamicin plus ketoconazole had a meaningful difference from mean results (standard), and from the second best mix (metronidazole plus nystatin), with a rapid itch healing, efficacy, and relapse decrease. Metronidazole plus nystatin had the highest score in tolerance and treatment period.
Conclusion: 90% of polled Latin-American obstetricians prescribe clyndamicin plus ketoconazole as the best available treatment to mixed vaginitis.


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