Villegas SR, Muro FR, Garduño EJ, Cuevas ML, Madrigal MO, Estrada FJV, García HJ

Language: Spanish
References: 42
Page: 51-59
PDF size: 83.54 Kb.

ABSTRACT

Neonatal sepsis has a frequency about 1 to 5 cases per 1000 newborns. Different risk factors are associated. For diag-nosis, hematological findings are the most frequent laboratory test employed. In this study we analyze the hematological findings related with sepsis etiology and risk factors.
Material and methods. A transversal study was done in a neonatal intensive care unit that attends newborns with medical and/or surgical diseases. There were included all newborns with suspected sepsis, a group was constituted by those with bacterial isolation, a negative control group was included. Results. 202 charts were reviewed. There were 142 cases and 60 controls. In 70 patients Staphylococcus were isolated, in 62 were isolated Gram negative bacilli and in 10 Candida sp. Leukocyte count had a median similar in cases and controls. The principal risk factors in newborns infected by Staphylococcus were low gestational age, low birth weight, central venous catheter, surgery and parenteral nutrition. For Gram negative bacilli long hospital stay, previous antimicrobial use, central venous catheter, metabolic acidosis, and immature/mature leukocyte ratio ›0.20.
Conclusion. Preterm newborn with low birth weight, long hospital stay, previous antimicrobial use, central venous catheter, metabolic acidosis, and immature/mature leukocyte ratio ›0.20 had a major risk for Gram negative sepsis.

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