Limón-Rojas AE, Reyna-Figueroa J, Wakida-Kusonoki G, Nava-Jácome R, Rivera I

Language: Spanish
References: 12
Page: 29-32
PDF size: 152.73 Kb.

ABSTRACT

Introduction. Hemophagocytic Syndrome (HPS) is a disorder in which histiocyte proliferation is associated to the phagocytosis of hematopoietic elements, producing heterogeneous clinical and paraclinical data. Epstein Barr virus and cytomegalovirus individually has been associatted to HPS.
Clinical case. We describe the case of a 9 year old child who presented an HPS reactive to Epstein-Barr and Cytomegalovirus infection. He has abdominal pain, fever, arthralgias and mialgias. Malaise, hepatosplenomegaly, pancytopenia and edema, and plasmatic cells in bone marrow aspirate.
He developed neurological and renal deterioration and death. The necropsy report described the presence of hemophagocytosis in tissues. PCR to Epstein-Barr virus and cytomegalovirus were reported positives.
Conclusions: HPS is associated to Epstein-Barr virus infection. The association of cytomegalovirus and Epstein Barr virus, is not reported, probabily the prognosis is poor, in patients with cytomegalic diseases associated to Epstein-Barr virus infection.

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