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2006, Number 4

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Enf Infec Microbiol 2006; 26 (4)

Cerebral trypanosomiasis in AIDS. Case report and literature review

Frías SJA, Moreno HNA, Cruz AE

Language: Spanish
References: 33
Page: 123-128
PDF size: 109.06 Kb.


ABSTRACT

A case patient female, complaining of headache, nausea, vomiting, somnolence, short memory problems, loss of weight and coma. T. cruzi were seen in a cerebrospinal, with Cryptococcus; multiple ring enhancing lesions on CT scan, died. T. cruzi infection of the CNS is a rare disease, but we have an increasing number of cases in HIV immunocompromised patients. Diagnosis by direct observation of CSF is uncommon; this article intends to include cerebral trypanosomiasis in the differential diagnosis of intracranial space-occupying lesions, especially in immunocompromised patients from endemic regions. This is first report in Mexico of Chagas´s related to an HIV infection with CNS involvement.


REFERENCES

  1. Prata A. Chagas’ disease. Infect Dis Clin N Am 1994; 8: 61-76.

  2. Kirchoff LV. American trypanosomiasis (Chagas disease). A tropical disease now in the United State. N Engl J Med 1993; 329: 639-644.

  3. Kirchoff LV, Gam AA, William FC. American trypanosomiasis (Chagas diseases) in Central American immigrants. Am J Med 1987; 329: 639-644.

  4. Norma Oficial Mexicana NOM-003-SSA2-1993. Para disposición de sangre humana y sus componentes con fines terapéuticos. Diario Oficial de la Federación, 8 de diciembre de 1993.

  5. Vallejo M, Reyes PA. American tripanosomiasis. A sociomedical problem in Mexico. Arch Inst Cardiol Méx 1996; 66: 95-97.

  6. Atias A. Enfermedad de Chagas digestiva en Chile, experiencia de 20 años. Bol Hosp. San Juan de Dios 1980; 27: 251-257.

  7. Hayes RJ, Schosield ChJ. Estimación de las tasas de incidencia de infecciones y parasitosis crónicas a partir de la prevalencia. Enfermedad de Chagas en América Latina. Bol Of Sanit Panam 1990; 108: 308-315.

  8. Dias JCP, Silveira AC, Schofield CJ. The impact of Chagas disease control in Latin America. A review. Mem Inst Oswaldo Cruz 2002; 97: 603-612.

  9. Ruesgsegger de Gutiérrez GL, Monteon VM, Reyes PA. American Trypanosomiasis (Chagas disease). A clinico serological survey in a rural community of Oaxaca. Arch Inst Cardiol Méx 1993; 63: 145-148.

  10. Martínez EVF, Frías SJA. Megaesófago chagásico. Informe de un caso. Rev Sanid Milit Méx 1997; 51: 181-182.

  11. Jiménez DX, Azoños GV, Torres CM, Guzmán BC. Seroprevalencia de anticuerpos anti T. cruzi en pacientes hemofílicos. XXVI Congreso AMIMC Guadalajara, Jal., Mex 2001: S80: c114.

  12. Martínez SE, Guzmán BC, Salmerón AM y cols. Factores de riesgo asociados a la infección por T. cruzi en localidades rurales del estado de Guerrero, México. XXVI Congreso AMIMC Guadalajara, Jal., Méx 2001: S78: c106.

  13. Barrera PMA, Rodríguez FME, Guzmán ME, Ramírez GMJ. Identificación de los triatomineos y conocimientos, prácticas y actitudes sobre la enfermedad de Chagas en la población de Eknacán, Yucatán, Méx. XXVI Congreso AMIMC Guadalajara, Jal., Méx 2001: S66: C58.

  14. Rodríguez FME, Barrera PMA, Ruiz PH y cols. Distribución geográfica de Triatoma dimidata e índices de infección por T. cruzi en la Península de Yucatán, México. XXVI Congreso AMIMC Guadalajara, Jal., Méx 2001: S52: C02.

  15. Hagar JM, Rhimtoola SH. Chagas Herat disease in the United State. N Engl J Med 1991; 325: 763-768.

  16. Pagano MA, Segura MJ, Di Lorenzo GA y cols. Cerebral Tumor-Like American Trypanosomiasis in Acquired Immunodeficiency Syndrome. Ann Neurology 1999; 45: 403-406.

  17. Antunes AC, Cechinni FM, Bolli FB y cols. Cerebral Trypanosomiasis and AIDS. Arq Neuro-Psiquiatr 2002; 60: 730-733.

  18. Corti M. AIDS and Chagas ‘disease. AIDS Patient Care & Stds 2000; 14(11): 581-588.

  19. Del-Castillo M, Mendoza G, Oviedo J, Pérez-Bianco RP, Anselmo AE, Silva M. AIDS and Chagas’ disease with central nervous system tumor-like lesion. Am J Med 1990; 88: 693-694.

  20. Gluckstein D, Ciferri F, Ruskin J. Chagas’ disease: another cause of cerebral mass in the Acquired Immunodeficiency Syndrome. Am J Med 1992; 92: 429-432.

  21. Metze K, Maciel JA. AIDS and Chagas’ disease. Neurology 1993; 43: 447-448.

  22. Oddo D, Casanova M, Acuna G, Ballesteros J, Morales B. Acute Chagas’ disease (Trypanosoma americana) in acquired immunodeficiency syndrome: report of two cases. Hum Pathol 1992; 23: 41-44.

  23. Rosemberg S, Chaves CJ, Higuchi ML, Lopes MBS, Castro LHM, Machado LR. Fatal Meningoencephalitis caused by reactivation of Trypanosoma cruzi infection in a patient with AIDS. Neurology 1992; 42: 640-642.

  24. Rodrigues D, Reis M, Teixeria V, Silva Vergara M, Filho DC, Adad S, Lazo J. Pathologic findings in the adrenal glands of autopsied patients with acquired immunodeficiency syndrome. Pathol, Res & Pract 2002: 198(1): 25-30.

  25. Villanueva MS. Trypanosomiasis of the central nervous system. Semin Neurol 1993; 13: 209-218.

  26. Hoff R, Teixeira R, Carvalho J, Mott KE. Trypanosoma cruzi in the cerebrospinal fluid during the acute stage of Chagas ‘disease. N Engl J Med 1978; 298: 604-646.

  27. Cohen JE, Tsai EC, Ginsberg HJ, Godes J. Pseudotumoral chagasic meningoencephalitis as the first manifestation of acquired immunodeficiency syndrome. Surg Neurol 1998; 49: 324-327.

  28. Calani L, Jayat G, Chiocconi E y cols. Central nervous system Chagas’s disease in HIV positive patients. Report two cases. XIII International AIDS 2000; Durban SA, TuPeB3172.

  29. Ferreira MS, Nishioka SA, Silvestre MT y cols. Reactivation of Chagas’s disease in patients with AIDS: Report of three new cases and review of the literature. CID 1997; 25: 1397-1400.

  30. Silva N, O’Bryan L, Medeiros E. y cols. Trypanosoma cruzi Meningoencephalitis in HIV-Infected Patients . J AIDS & Hum Retrov 1999; 20: 342-349.

  31. Montero A, Cohen JE, Martínez DP, Giovannoni AG. Tratamiento empírico anti toxoplasma en SIDA y Chagas cerebral. Relato de dos casos, revisión de la bibliografía y propuesta de un algoritmo. Medicina (Buenos Aires) 1998; 58: 504-506.

  32. Corti ME. www.siisalud.com/des/des033/03912000.htm

  33. Chirinos Y, León B, Díaz M y cols. Tripanosomiasis americana cerebral en un paciente con SIDA; diagnosticado por examen directo y confirmado por reacción de polimerasa en cadena en líquido cefalorraquídeo. Chagaspcvc@ fac.org.ar




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