2006, Number 2
Diagnostic utility of percutaneous aspiration needle biopsy in a pediatric service
López-Ibarra S, Calderón-Elvir C, Braun-Roth G, Ridaura-Sanz C, Medina-Vega A
Language: Spanish
References: 8
Page: 69-72
PDF size: 132.77 Kb.
ABSTRACT
Introduction: There is no doubt that the citopayologic diagnosis of tumoral cels, of any origin in adults, by realizing an aspiration needle biopsy is a common practice and of high utility. However in a pediatric age is rarely done.Material and methods: prospective, prolective , observational and comparative. Ultrasound was realized and or computed tomography to every patient with a high diagnosis of a solid tumor at the first consult. Afterwards de fine needle biopsy aspiration was done and an open biopsy at the surgical ward. Hematoxilin and eosin was applied to every biopsy , when there was doubt of the diagnosis Inmunohistoquimical studies were realized. Results were compared.
Results: Whe had 21 patients, 12 male and 9 female. Ages ranging from 1 day to 173 months, with a median of 67.6months. The anatomical site of the tumor was: abdominal in 9 cases, extremities in 5, and neck in 4, Thorax 1, pelvis 1, sacrococcigeal 1. In 3 patients (14.3%), the needle biopsy had no use excluding the following results( total of 18). To make a precise diagnosis of malignant tumors versus benign, the needle biopsy had a sensivity and specificity, negative and positive predictive value of 100%, similar to open biopsies. Eventhough to make a better diagnosis of malignancy, it diminished to a value of 38%( five patients). The open biopsy continued at 100%. When Inmunohistoquimical studies were realized to aspiration needle biopsy, the value was elevated to 100%.
Conclusion: the fine needle biopsy aspiration with the help of inmunohistoquimicalstudies offers a precise diagnosis in solid malignant tumors, giving good reasons to use fine needle biopsy aspiration biopsy as a first line diagnosis.
REFERENCES