2010, Number 4
<< Back Next >>
Rev Mex Anest 2010; 33 (4)
Variaciones del magnesio sérico en cirugía cardiovascular con derivación cardiopulmonar (DCP)
Ortiz CJL, Gallardo LNM, Ortega PS, Mendoza de la V HE, Lozano NR, González OSA
Language: Spanish
References: 22
Page: 200-206
PDF size: 506.00 Kb.
ABSTRACT
There were studied 80 patients who were scheduled for cardiovascular surgery and required cardiopulmonary derivation. The were performed magnesium seric determinations three times on each one of them, the firstone as basal sample before getting to the surgery room, the second one during the cardiopulmonar derivation and the last one when they left the surgery room. The purpose was to observe the variations that can happen during the perioperative and the electrocardiography and hemodynamic complications that result from the various determinations. The result will be known at the end of the surgery for not to modify the transanesthetic handling. The performed surgeries were: 16 of valve mitral, 21 for valve aortic, 19 of bypass coronary, 7 of valves tricuspid, 13 combined surgeries and 4 congenital heart disease 1 Jatene, 1 Fontan and 2 interear communication (CIA). The Result: Was obtained from the first basal sample was
p = 0.002954, from the second sample was
p = 0.00014 and from the final sample was
p = 0.237423. These results gives us a significative value, by the test of Mann-Whitney of 0.000061 and by the test of ANOVA for treatments of 0.000020, being statistically significant.
Conclusion: A last of magnesium exists during the transurgery that produce hypomagnesemia that is greater after the cardiopulmonary derivation and this causes heart arrhythmias and hemodynamics instability.
REFERENCES
Fawcett WJ, Haxby EJ, Male DA. Magnesium: physiology and pharmacology. Br J Anaesth 1999;83:302-20.
Abraham A. Potassium and magnesium concentrations as prognostic factors after acute myocardial infarction. Cardiology 1988;75:194-9.
Porrata MC, Hernández T, Argüelles V. Recomendaciones nutricionales y guías de alimentación para la población cubana. La Habana: Editorial Pueblo y Educación; 1986.
Marano L, Bestetti A, Louinscio A, Tagliabue L, Castini D, Dario P, et al. Effects of infusion of glucose – insulin – potassium on myocardial function after a recent myocardial infarction. Acta Cardiol 2000;55:9-14.
Luderitz B, Manz M. The value of magnesium in intensive care. Borm Z Kardiol 1994;83:121-6.
Spisak, V. Treatment of acute myocardium infarct with magnesium. Unitr Lek 1994;40:649-53.
Woods KL, Fletcher S. Long term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester intravenous (magnesium intervention trial LIMIT 2). Lancet 1994;343:816-9.
Hiroki K, Toshiya K, Hitoshi K, Masaru M. Three-day magnesium administration prevents atrial fibrillation after coronary artery bypass grafting. Ann Thorac Surg 2005;79:117-26.
Forlani S, Moscarelli M, Scafuri A, Pellegrino A, Chiariello L. Combination therapy for prevention of atrial fibrillation after coronary artery bypass surgery: a randomized trial of sotalol and magnesium. Card Electrophysiol Rev 2003;7:168-71.
Casthely PA, Yoganathan T, Komer C, Kelly M. Magnesium and arrhythmias after coronary artery bypass surgery. J Cardiothorac Vasc Anesth 1994;8:188-91.
Lu CY, Tan PH, Lin SH, Tsai SK, Lin SM, Mao CC, Yang LC. Body weight – related ionized hypomagnesemia in pediatric patients undergoing cardiopulmonary bypass for surgical repair of congenital cardiac defects. J Clin Anesth 2003;15:189-93.
Speziale G, Ruvolo G, Fattouch K, Macrina F, Tonelli F, Donnetti M, Marino B. Arrhythmia prophylaxis after coronary artery bypass grafting: regimens of magnesium sulfate administration. J. Thorac Cardiovasc Surg 2000;48:22-6.
Shakerinia T, Ali IM, Sullivan JA. Magnesium in cardioplejia: is it necessary? Can J Surg 1996;39:397-400.
Aglio LS, Stanford GG, Maddi R, Boyd JL 3rd, Nussbaum S, Chernow B. Hypomagnesemia is common following cardiac surgery. J Cardiothorac Vasc Anesth 1991;5:197-202.
Wisthaka JO, Koistinen J, Karlqvist KE, Lepojarvi MV, Hanhela R, Laurila J, Nissinen J, et al. Magnesium substitution in elective coronary artery surgery: a double blind clinical study. J Cardiothorac Vasc Anesth 1995;9:140-6.
Aziz S, Haigh WG, Van Norman GA, Kenny RJ, Kenny MA. Blood ionized magnesium concentrations during cardiopulmonary bypass and their correlation with other circulating cations. J Card Surg 1996;11:341-7.
Harris MN, Crowther A, Jupp RA, Aps C. Magnesium and coronary revascularization. Br J Anaesth 1988;60:779-83.
Steinberger HA, Hanson CW 3 rd. Outcome – based justification for implementing new point – of – care test: there is no difference between magnesium replacement based on ionized magnesium and total magnesium as a predictor of development of arrhythmias in the postoperative cardiac surgical patient. Clin Lab Manage Rev 1998;12:87-90.
Wilkes NJ, Mallet SV, Peachev T, Di Salvo C, Walesby R. Correction of ionized plasma magnesium during cardiopulmonary bypass reduces the risk of postoperative cardiac arrhythmia. Anesth Analg 2003;96:1838-1843.
Nickole N, Effie L, White M, Kluger J, Coleman C. Impact of intravenous magnesium on post – cardiothoracic surgery atrial fibrillation and length of hospital stay: A Meta – analysis. Ann Thorac Surg 2005;80:2402-2406.
Toshiya S, Zen´ichiro W, Tetsuo I, Ryo O. Magnesium prophylaxis for arrhythmias after cardiac surgery: A meta – analysis of randomized controlled trials. Am J Med 2004;117:325-333.
Wong E, Rude R, Singer F, et al. A high prevalence of hypomagnesemia and hypermagnesemia in hospitalized patients. Am J Clin Pathol 1983;79:348-52.