Avilés-Aguilar A , Ibarra TA , Rivera-Salgado MI

Language: Spanish
References: 10
Page: 258-260
PDF size: 127.18 Kb.

ABSTRACT

Objective and importance: primary melanoma of the CNS it’s a rare condition; we report the case of a primary malignant melanoma of the left trigone that radiographically mimicked a metastatic lesion. Clinical presentation: a 51-year-old female with antecedents of tabaquism and depression. Two weeks of headache, nausea and vomiting, neurological work-up revealed a large tumor of the left trigone radiographically diagnosed as a metastatic lesion. Intervention: a transcortical approach by de second temporal circumvolution revealed a pigmented, vascular neoplasm in the left ventricular trigone. The tumor was totally macroscopically resected and histopathological diagnosis of melanoma was made. The patient had no history of cutaneous or ocular melanoma and no other site of disease was ever discovered. The patient had a good neurological outcome no tumoral recurrence was found in a two year follow up. Conclusion: the case most likely represents primary melanoma of the central nervous system that mimicked a metastatic neoplasm; the differential diagnosis of the ventricular trigone neoplasms is discussed as are the prognostic implications of primary melanoma of the CNS.

REFERENCES

1. Castro S. Soffetti R. Bradac G, Boldorini R. Primitive cerebral melanoma: case report and review of the literature. Surg Neurol 2001; Mar;55(3):163-8;

2. Piedra M, Scheithauer B, Driscoll C, Link M. Primary melanocytic tumor of the cerebellopontine angle mimicking a vestibular schwannoma: case report. Neurosurgery 2006; Jul; 59(1):E206; discussion E206.

3. Ferraresi V. Cognetti F. Central nervous system as exclusive site of disease in patients with melanoma: treatment and clinical outcome of two cases. Melanoma Research 2005; 15:467-9.

4. Waldron J, Tihan T. Epidemiology and pathology of intraventricular tumors. Neurosurg Clin N Am 2003;14:469-82.

5. Mizuno M. Renal cell carcinoma metastasizing to choroid plexus of lateral ventricle; a case report. No Shinkei Geka 1992; 20(4):469-74.

6. Tanimoto M. Choroid plexus metastasis of lung carcinoma-case report. Neurol Med Chir (Tokyo) 1991; 31(3):152-5.

7. Nakabayashi H. Choroid plexus metastasis from gastric cancercase report. Neurol Med Chir (Tokyo) 1994; 34(3):183-6.

8. Piniella AM, Siatkowski RM. Adrenal cortical carcinoma metastatic to the brain in a child. J Neuro-ophthalmol 2000; 20(1):35-7.

9. Qasho. Choroid plexus metastasis from carcinoma of the bladder: case report and review of the literature. J Neurooncol 1999; 45(3):237-40.

10. D. Angelo V, Galarza M, Catapano D, Monte V, Bisceglia M, Carosi I. Lateral ventricle tumors: surgical strategies according to tumor origin and development a series of 72 cases Neurosurgery 56[ONS Suppl 1]:ONS-36-ONS-45,2005.