Pereyra NTA, Yáñez GI, Reyes VL

Language: Spanish
References: 22
Page: 13-18
PDF size: 349.81 Kb.

ABSTRACT

Background: Periodontal disease in patients with HIV infection is frequent and with great morbidity specially with major immune suppression. Superinfections are not well studied in developing countries. The study objective is to know the frequency of periodontal disease caused by superinfecting microorganisms in our population of HIV patients. Methods: Prospective cohort study. We studied 97 HIV patients with ‹ 200 CD4+ cells/mL. We evaluated the presence of periodontal disease. In those patients, we took samples from the periodontal pockets and gum biopsies for microbiological analysis for other microbes than those common causes of periodontitis. Results: Mean CD4+ T cells were of 112 and viral load of 55,000. All patients were on HAART. 59.7% (58/97) had periodontal disease. 31% (18/97) had gingivitis with associated factors as: Malnutrition 16.6% and smoking 55.5%. 38.8% of the patients with gingivitis had linear gingival erythema. From the patients with periodontal disease, Candida species were isolated in 29.3% (17). C. albicans in 12, C. krusei in 3 and C. tropicalis and C. guillermondi with one isolate each one. 27.5% of patients with periodontal disease had bacterial isolates (16), E. coli in 7, P. aeruginosa in 5, polimicrobial flora in 4 (E. coli, K. pneumoniae and E. cloacae). Conclusions: The periodontal disease frequency was of 59.7%. Chronic periodontitis was more frequent than gingivitis. The more frequent isolates in one third of the patients were for Candida albicans and for bacterias, Escherichia coli. Periodontal disease caused by superinfecting microorganisms is frequent in HIV+ patients.

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