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2005, Number 72

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Rev Enfer Infec Pediatr 2005; 18.19 (72)

Human cytomegalovirus defection in paediatric patient

Navarrete DN, Villanueva MM, Manilla TEÁ, García GR

Language: Spanish
References: 25
Page: 90-96
PDF size: 152.63 Kb.


ABSTRACT

Cytomegalovirus infection still being a serius complication in solid organ and bone marrow transplant recipients and patients immunocompromised. In the last years, great advances have been made in the diagnosis of cytomegalovirus infection. It was studied by qualitative determination of pp67 mRNA by nucleic acid sequence based amplification (NASBA), antigenemie (pp65) and detection of Ig G and Ig M, one series of 65 patients. The prevalence of evidence of CMVH infection in 65 patients was high in ‹ 1 to 5 years old. The positivite of antigenemia, NASBA, IgG and IgM were 92,53,62 and 100%, respectively. In conclusion, it’s clear from our results that the antigenemia is positive more frequently that the NASBA assay and the NASBA assay was able to distinguish infection from disease in 19 patients.


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