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2010, Number S1

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Rev Mex Med Transfus 2010; 3 (S1)

Clinical use of plasma and plasmatic derivated

Paredes AR

Language: Spanish
References: 18
Page: 87-91
PDF size: 147.69 Kb.


ABSTRACT

Plasma and plasma fractions have specific, limited indications and should not be used indiscriminately. Specific coagulation defects should be treated with specific plasma fractions, not FFP. FFP is not indicated for volume replacement. FFP and cryoprecipitate should not be used for prophylaxis or for abnormal coagulations test in the abscense of bleeding. Large-scale, prospective, randomized trials are needed to clarify the efficacy of plasma and plasma products in many clinical settings. An inexpensive means of pathogen elimination is needed. Expanded knowledge of the interactions between coagulation factors and the endothelial cell surface will help focus future clinical research.


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